FREE AND STUDY GAMES ABOUT IMMUNO CH 7 EXAM

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FREE AND STUDY GAMES ABOUT IMMUNO CH 7 EXAM

QUESTIONS

Qs and Ans Expert- Explanation

This Exam contains:

-Guarantee passing score -132 Questions and Answers -format set of multiple-choice -Expert- Explanation Question 1: True or false: DAF dissociates complement C3b from RBCs

Answer:

True

Question 2: Serum proteins involved in the MBL pathway?

Answer:

• MBL

- MASP-1

- MASP-2

Question 3: Complement can be harmful if:

Answer:

• activated systemically on a large scale, as in gram-negative septicemia
• activated by tissue necrosis, as in myocardial infarction
• lysis of RBCs occurs

Question 4: What takes place as a result from a change that takes place as C1q is bound?

Answer:

Autoactivation of C1r

Question 5: What are the immunoglobulin or antibody isotypes?

Answer:

IgG, IgM, IgA, IgD, IgE Question 6: Found in both classical and alternative pathways:

• Properdin
• C2
• Factor D
• C3

Answer:

C3 Question 7: C1 components are mainly produced by:

Answer:

Intestinal epithelial cells Question 8: WBCs are additional sources of early complement components:

Answer:

C1-4 Question 9: The alternative pathway is activated by:

Answer:

C3b

Question 10: C4, C2, and C3 are which stage?

Answer:

Activation

Question 11: Which best describes the role of CR2 on cell membranes

• binds C1prs to inactivate it
• acts as co-receptor on B cells for antigen
• increases clearance of immune complexes
• Binds particles opsonized with C3b

Answer:

Acts as co-receptor on B cells for antigen

Question 12: Which of the following is referred to as C3 convertase?

• C1prs

B C3bD

• C3bBb
• C4b5a

Answer:

C3bBb Question 13: A deficiency in C5-C8 is associated with:

Answer:

Neisseria injections

Question 14: C5 convertase (classical pathway)

• C4b2a3b
• C4b2a
• C3bBb3bP
• C1qrs

Answer:

C4b2a3b

Question 15: All of the following are true of the recognition unit EXCEPT:

• it consists of C1q, C1r, C1s
• the subunits require calcium for binding together
• binding occurs at the FC region of antibody molecules
• C1q becomes active esterase

Answer:

C1q becomes an active esterase

Question 16: What is the source of C1-4?

Answer:

WBCs (monocytes and macrophages) Question 17: MAC:

• C4, C5, C6
• C5b, C6, C7, C8, C9
• C6, C7, C8, C9
• C2, C3, C4, C5, C6

Answer:

C5b, C6, C7, C8, C9

Question 18: What are the three pathways?

Answer:

• classical
• lectin
• alternative

Question 19: The lectin pathway involves three classes of recognition molecules

Answer:

• lectins
• ficolins

- CL-L1