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FREE AND STUDY GAMES ABOUT IMMUNO CH 7 EXAM
QUESTIONS
Actual Qs and Ans Expert-Verified Explanation
This Exam contains:
-Guarantee passing score -132 Questions and Answers -format set of multiple-choice -Expert-Verified Explanation Question 1: True or false: DAF dissociates complement C3b from RBCs
Answer:
True
Question 2: Serum proteins involved in the MBL pathway?
Answer:
- MBL
- MASP-1
- MASP-2
Question 3: Complement can be harmful if:
Answer:
- activated systemically on a large scale, as in gram-negative septicemia
- activated by tissue necrosis, as in myocardial infarction
- lysis of RBCs occurs
Question 4: What takes place as a result from a change that takes place as C1q is bound?
Answer:
Autoactivation of C1r
Question 5: What are the immunoglobulin or antibody isotypes?
Answer:
IgG, IgM, IgA, IgD, IgE Question 6: Found in both classical and alternative pathways:
- Properdin
- C2
- Factor D
- C3
Answer:
C3 Question 7: C1 components are mainly produced by:
Answer:
Intestinal epithelial cells Question 8: WBCs are additional sources of early complement components:
Answer:
C1-4 Question 9: The alternative pathway is activated by:
Answer:
C3b
Question 10: C4, C2, and C3 are which stage?
Answer:
Activation
Question 11: Which best describes the role of CR2 on cell membranes
- binds C1prs to inactivate it
- acts as co-receptor on B cells for antigen
- increases clearance of immune complexes
- Binds particles opsonized with C3b
Answer:
Acts as co-receptor on B cells for antigen
Question 12: Which of the following is referred to as C3 convertase?
- C1prs
- C3bBb
- C4b5a
B C3bD
Answer:
C3bBb Question 13: A deficiency in C5-C8 is associated with:
Answer:
Neisseria injections
Question 14: C5 convertase (classical pathway)
- C4b2a3b
- C4b2a
- C3bBb3bP
- C1qrs
Answer:
C4b2a3b
Question 15: All of the following are true of the recognition unit EXCEPT:
- it consists of C1q, C1r, C1s
- the subunits require calcium for binding together
- binding occurs at the FC region of antibody molecules
- C1q becomes active esterase
Answer:
C1q becomes an active esterase
Question 16: What is the source of C1-4?
Answer:
WBCs (monocytes and macrophages) Question 17: MAC:
- C4, C5, C6
- C5b, C6, C7, C8, C9
- C6, C7, C8, C9
- C2, C3, C4, C5, C6
Answer:
C5b, C6, C7, C8, C9
Question 18: What are the three pathways?
Answer:
- classical
- lectin
- alternative
Question 19: The lectin pathway involves three classes of recognition molecules
Answer:
- lectins
- ficolins