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FREE USMLE AND STUDY GAMES ABOUT MICROBIOLOGY

Class notes Jan 11, 2026
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FREE USMLE AND STUDY GAMES ABOUT MICROBIOLOGY

EXAM QUESTIONS

Actual Qs and Ans Expert-Verified Explanation

This Exam contains:

-Guarantee passing score -365 Questions and Answers -format set of multiple-choice -Expert-Verified Explanation Question 1: In the lab, how do you differentiate Neisseria meningitidis from gonorrhoeae?

Answer:

Meningitidis ferments maltose, whereas gonorrhoeae doesn't

Question 2: What are the 3 groups of Gram positive cocci

Answer:

Streptococcus, Staphylococcus and Enterococcus

Question 3: What receptor and coreceptors are used by HIV?

Answer:

receptor: CD4, coreceptor in macrophages (early infection) CCR5, in T cells (late infection) CXCR4

Question 4: Food poisoning associated with potato salad

Answer:

Heat stable enterotoxin of Staph. aureus

Question 5: Surgical wound from C section becomes red, painful and hot, most common CA

Answer:

Staph. aureus Question 6: CD4 count expected in AIDS patient with Pneumocystis jirovecii pneumonia

Answer:

< 50

Question 7: Tissues infected by the genus Microsporum

Answer:

Skin, hair

Question 8: HIV pt at risk of toxoplasma when CD4 falls below what number?

Answer:

100 Question 9: 19 year old patient reports low fever, dry cough, chest X ray shows diffuse infiltrates, patient says the cough won't let her sleep.

Answer:

Mycoplasma pneumoniae

Question 10: Name 2 coagulase positive bacteria

Answer:

Staph. aureus and Yersinia pestis

Question 11: How are multidrug resistance plasmids created?

Answer:

By adding up multiple transpositional recombination events in the same plasmid

Question 12: Infections that cross the placenta (TORCH)

Answer:

Toxoplasma, Other (Syphilis), Rubella, CMV, HIV and Herpes

Question 13: What are the DNA viruses? (Pardon Papa As He Has Pox)

Answer:

Parvovirus, Papilloma and Polyomavirus, Adenovirus, Hepadnavirus (Hep B), Herpes virus (HSV, VZV, EBV, CMV, HHV6, and HHV8), and Poxvirus (Variola, Vaccinia, Molluscum contagiosum)

Question 14: Vaccinated teenager with meningitis and rash

Answer:

Neisseria meningitidis (vaccine not that effective)

Question 15: Name 2 endospore forming bacteria

Answer:

Clostridium and Bacillus

Question 16: Mechanism of action of tetanus toxin

Answer:

Binds to ganglioside in synaptic membrane blocking release of glycine and GABA

Question 17: Drug of choice for most meningitis

Answer:

third generation cephalosporin

Question 18: Two bacteria linked to HUS

Answer:

EHEC and Shigella

Question 19: CA of bacillary angiomatosis

Answer:

Bartonella henseslae Question 20: AIDS patient develops dry cough and hypoxia, chest X-ray shows ground-glass pattern, bronchoalveolar lavage stained on H&E shows honeycomb looking exudate

Answer:

Pneumocystis jiroveci

Question 21: Top cause of meningitis in immigrant 6 month old

Answer:

Hib

Question 22: meningitis causing pleomorphic Gram negative rods

Answer:

Haemophilus influenzae Question 23: Pathogenic factor of Influenza A virus that is responsible for pandemics

Answer:

Antigenic shift

Question 24: Mechanism of action of Pseudomonas exotoxin A and diphtheria toxin

Answer:

ADP ribosylation of eEF-2 --> inhibition of protein synthesis

Question 25: Whiff test aids in the diagnosis of

Answer:

Gardnerella vaginalis Question 26: What do you need to interpret a Kirby-Bauer agar disc diffusion test?

Answer:

Key Question 27: What is the reservoir for Salmonella typhi? and for the non-typhi species?

Answer:

Typhi: humans. Non-typhi: animals (think poultry)

Question 28: What are the two body forms (and their functions) of Chlamydia?

Answer:

Elementary body (infectious, enters the cell), Reticular (replicates inside the cell)

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