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1. What is the first-line treatment for H. pylori infection?
 A. Amoxicillin
 B. Clarithromycin
 C. Metronidazole
 D. Tetracycline
 **Answer: B. Clarithromycin**
 Rationale: Clarithromycin-based triple therapy is considered the firstline treatment for H. pylori infection.
2. Which medication is not typically used in triple therapy for H. pylori?
 A. Amoxicillin
 B. Bismuth subsalicylate
 C. Levofloxacin
 D. Omeprazole
 **Answer: C. Levofloxacin**
 Rationale: Levofloxacin may be used as a second-line treatment, but it is
not typically part of the initial triple therapy regimen.
3. For a patient with a penicillin allergy, which medication can be
substituted in the H. pylori treatment regimen?
 A. Metronidazole
 B. Clarithromycin
 C. Tetracycline
 D. Levofloxacin
 **Answer: A. Metronidazole**
 Rationale: Metronidazole can be used as an alternative to amoxicillin in
patients with a penicillin allergy.
4. What is the role of PPIs in the treatment regimen of H. pylori?
 A. To relieve symptoms
 B. To reduce acid production
 C. To enhance antibiotic efficacy
 D. All of the above
 **Answer: D. All of the above**
 Rationale: PPIs reduce gastric acid production, which helps relieve
symptoms and enhances the efficacy of antibiotics.
5. Which statement is true regarding quadruple therapy for H. pylori?
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