HESI PHARMACOLOGY PRACTICE TEST ASSESSMENT WITH VERIFIED ANSWERS AND RATIONALES

HESI PHARMACOLOGY PRACTICE TEST ASSESSMENT WITH VERIFIED ANSWERS AND RATIONALES
What pathophysiological action supports the expected outcome for a
client with chronic cancer pain who is treated with imipramine (Tofranil),
a tricyclic antidepressant?
Increases pain threshold by stimulating opiate receptors in the CNS to release of
endogenous enkephalins.
Decreases perception of pain by blocking opiate receptors in the brain and
descending inhibitory nerves.
Decreases transmission of pain impulses by altering serotonin and
norepinephrine activity at nerve synapses.
Increases pain tolerance through relief of depression by increasing the amounts
of norepinephrine in the brain.
Rationale
Tricyclic antidepressants reduce neuropathic pain due to cancer invasion by blocking the reuptake of
serotonin and norepinephrine in the CNS, and thereby inhibit pain transmission in the spinal cord dorsal
horn, which are part of the descending pain-modulating system.
Page 2 of 42
A 48-year-old client is experiencing a severe anaphylactic reaction to an
injection of contrast media. What pharmacologic agent is of greatest use
in this situation?
Dopamine (Intropin).
Loratadine (Claritin).
Nitroprusside (Nipride).
Epinephrine (Adrenalin).
Rationale
Epinephrine is the drug of choice in treating hypotension and circulatory failure associated with
anaphylaxis because it is a potent vasoconstrictor. An anaphylactic reaction is an acute systemic
hypersensitivity reaction that occurs within minutes of antigen exposure (such as with contrast material
containing iodine) that can result in peripheral vascular collapse.
What teaching should the nurse provide a client who has received a new
prescription for sildenafil (Viagra)? (Select all that apply.)
Select all that apply
Frequent use can lead to the development of hypertension.
Most effective if taken after at least 6 hours of REM sleep.
Take within 30 to 60 minutes of sexual stimulation.
Report rebound priapism that occurs for 4 hours or more.
Can cause facial flushing and headache.
Page 3 of 42
Rationale
Sildenafil (Viagra) enhances the natural response to sexual stimuli, so a client should be instructed to
take Viagra within 30 to 60 minutes before sexual intercourse to provide adequate time to enhance
penile erection. Sildenafil does not cause erection directly, but priapism can occur and should be
reported to the healthcare provider if it persists. Common side effects include headaches, facial flushing,
and diarrhea. Viagra can potentiate vasodilators, such as alpha-adrenergic blockers, nitroglycerin, and
other nitrates used for angina pectoris, and may cause hypotension, which decreases perfusion to vital
organs.

HESI PHARMACOLOGY Exam,HESI PHARMACOLOGY Test,HESI PHARMACOLOGY Flashcard,HESI PHARMACOLOGY quiz,HESI PHARMACOLOGY Practice,HESI PHARMACOLOGY Practice test,HESI PHARMACOLOGY Practice flashcard,HESI PHARMACOLOGY Practice exam,HESI PHARMACOLOGY Study guide,HESI PHARMACOLOGY Practice questions,HESI PHARMACOLOGY Questions,HESI PHARMACOLOGY Practice questions and answers,HESI PHARMACOLOGY Questions and answers,HESI PHARMACOLOGY pdf,HESI PHARMACOLOGY quizlet,HESI PHARMACOLOGY reddit,HESI PHARMACOLOGY Answer sheet,HESI PHARMACOLOGY Answer key,HESI PHARMACOLOGY Pdf free,HESI PHARMACOLOGY Exam help,HESI PHARMACOLOGY Cheat sheet,HESI PHARMACOLOGY quiz bank,HESI PHARMACOLOGY Questions bank,HESI PHARMACOLOGY Practice Guide,HESI PHARMACOLOGY Guide,HESI PHARMACOLOGY Testbank,HESI PHARMACOLOGY Practice Answers,HESI PHARMACOLOGY Answers,HESI PHARMACOLOGY Exam prep,HESI PHARMACOLOGY Prep,HESI PHARMACOLOGY Pdf download,HESI PHARMACOLOGY Flashcards,HESI PHARMACOLOGY Real questions,HESI PHARMACOLOGY Actual questions,HESI PHARMACOLOGY Real Questions and answers,HESI PHARMACOLOGY Actual Questions and answers,HESI PHARMACOLOGY Exam review,HESI PHARMACOLOGY Review,HESI PHARMACOLOGY Exam questions,HESI PHARMACOLOGY Exam questions and answers,HESI PHARMACOLOGY Practice test pdf,HESI PHARMACOLOGY Practice test quizlet,HESI PHARMACOLOGY Practice test Reddit,HESI PHARMACOLOGY Practice test quizlet multiple choice,HESI PHARMACOLOGY Exam study guide,HESI PHARMACOLOGY Practice test free,HESI PHARMACOLOGY Test questions,HESI PHARMACOLOGY Exam study guide,HESI PHARMACOLOGY Practice exam free,HESI PHARMACOLOGY Practice tests free,HESI PHARMACOLOGY Exam practice test,HESI PHARMACOLOGY Exam test questions,HESI PHARMACOLOGY Exam questions and answers,HESI PHARMACOLOGY Exam practice test