HTHRHSC 5500 Concepts Assessment 1 Exam

HTHRHSC 5500 Concepts Assessment 1 Exam
Darrell Johnson is a 30 year-old man, who sustained a fracture of his left tibia 2 months
ago. The cast has just been removed, and he is amazed at the degree to which the
muscles in his leg have shrunk. What are the reasons for this muscle cell atrophy?
Select all correct responses.
This muscle cell atrophy is adaptive and reversible.
This muscle cell atrophy is a pathological response due to denervation.
This muscle cell atrophy is a physiological response due to disuse.
About 50% of males over age 60 develop benign prostatic hyperplasia as a result of the
excessive release of androgens. The hyperplasia may increase to such an extent that
the prostate, which encircles the urethra, can cause urethral narrowing resulting in a
slow or weak urine stream, hesitancy in starting urine flow, and frequent urge to urinate.
What are the characteristics of hyperplasia? Select all correct responses.
Cellular hyperplasia occurs when there is activation of the genes controlling cell
proliferation and the intracellular messengers that control cell replication and growth.
Physiologic hyperplasia occurs in response to a stimulus and ends after the stimulus is
removed; i.e., removal of the stimulating hormone.
Hyperplasia can only occur in cells capable of mitotic division.
Cellular hyperplasia is an increase in number of cells in a tissue or organ.
Sylvia Lewis is a 62-year-old woman, who has smoked cigarettes most of her adult life.
She notices that she is more prone to respiratory tract infections. What type of cellular
changes occur in the pulmonary airways when the ciliated columnar epithelial cells that
are exposed to the chronic irritation of cigarette smoke are replaced by stratified
squamous epithelial cells?
Metaplasia
What are the causes of intracellular accumulations? Select all that apply.
environmental agents that cannot be metabolized and removed from the cell
inability of cell to metabolize an endogenous product due to blockage of a metabolic
pathway
rate of cellular metabolism inadequate to remove excess of normal cell products

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