MKSAP – Neurology 100?curate A+ Review Q&A 2026/2027 (23pages)

Haldol is absolutely contraindicated in Dementia with Lewy bodies. What medication is a safer alternative in these patients? - Answer-Donepezil. May improve behavioral and cognitive symptoms with dementia. Parkinson's: medication used is carbidopa-levodopa What are common levodopa-related complications? - Answer-Motor fluctuations (caused by wearing off of the beneficial effects before next dose is administered) Medication-induced dyskinesia (involuntary choreic movements) Can also have nausea and orthostatic hypotension What is indicated for pts who have advanced Parkinson's who derive continued benefit from carbidopalevodopa but have med-related side effects? - Answer-Deep brain stimulation Meds that wouldn't be so great here... Apomorphine = fast-acting subq dopamine agonist. Indicated for rapid relief of sx caused by sudden wearing off of Parkinson's meds Droxidopa = for neurogenic orthostatic hypotension