NBME CBSE ACTUAL TEST QUESTIONS AND ANSWERS TEST BANK - COMPLETE SOLUTION RATED A

NBME CBSE ACTUAL TEST QUESTIONS AND ANSWERS TEST BANK - COMPLETE SOLUTION RATED A
1. 36-year-old F with 2 week history of fatigue, bleeding of the
gums, and bone pain. Physical examination shows pallor,
hepatosplenomegaly, and ecchymotic lesions over extremities.
Labs:Hb 8g/dlHt 25%Leukocytes: 36,000segm neutr
4%eosinophils 4%lymph 6%mono 6% promyelo 80%platelets
25,000Polymerase chain reaction test shows an mRNA
corresponding to the retinoic acid receptor- alfa/promyelocytic
leukemia fusion gene resulting from a reciprocal translocation of
chromosomes 15 and 17. Treatment w/ all-trans retinoic acid is
started. In response to the therapy, the fusion protein will most
likely attract which of the following proteins to form a pretranscriptional complex?
a. Histone acetylase
b. Histone acetylation allows for relaxation of the DNA
e. Histone Acetylation makes DNA Active

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