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NR 325 Endocrine Disorders – Worksheet

NR AND NUR Exams Jan 22, 2025
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NR 325 Endocrine Disorders – Worksheet

Please fill-up the columns below with major take-away or focus points for each topic/disorder. Review materials from previous courses such as Pathophysiology, etc.
Disorder/s Etiology/Pathophysiology
(Possible Causative and
Risk Factors)
Clinical Manifestations Diagnostic Tests Nursing Interventions and
Collaborative
Management
Possible Complications
and
Treatments/Interventio
ns for Complications
1
Diabetes Mellitus Type I
Rapid acting: Ex: lispro
(Humalog), aspart
(Novolog)
Onset: 10-30 min,
peak:30 min-3hr,
duration: 3-5 hr
Short acting: Ex: regular
(Humalin R, Novalin R)
Onset: 30 min-1hr, peak:
2-5 hr, duration: 5-8 hr
-ONLY INSULIN THAT
CAN BE GIVEN IV
Intermediate: Ex: NPH
(cloudy-Humulin N,
Novalin N)
Onset: 1.5-4 hr, peak: 4-
12 hr, duration: 12-18hr
Long Acting (nighttime):
Ex: glargine (Lantus),
detemir (Levemir), and
degludec (Tresiba)
Onset:0.8-4hr, peak:
NONE, duration: 12-24hr
 Destruction of beta cells
in pancreas due to
autoimmune
dysfunction.
 Patients are insulin
dependent.
 Onset in people younger
than 40 yrs but it can
occur in any age.
 Risk factors:
Genetics
Ethnicity (Hispanic, African,
Asian)
Insulin administration:
-absorption is fastest from
abdomen, then arm, thigh,
and buttock. Rotate sites.
SubQ so injects at 45-90
degree angle.
Insulin pump: continuous
infusion connected into subQ
tissue of abdominal wall.
Storage of insulin: do not
heat/freeze, in-use can be left
at room temp for 4wks, extra
should be refrigerated, avoid
exposure to direct sunlight,
extreme cold,
 Ketoacidosis
 Weight loss
 3 p’s: Polydipsia,
polyuria, & polyphagia
 Weakness
 Fatigue
 Hx & physical
examination
 HgbA1C of 6.5 or
higher
 Fasting plasma glucose
 Fructosamine
 Random plasma
glucose of 200 mg/dL
or greater
 Serum creatine
 Electrolytes
 Islet cell
autoantibodies
For exercise: eat carbs
before if BG is <100
Monitor levels frequently
Assess level of consciousness
Hydrate with hypertonic
solution
Administer insulin
Keep patient hydrated
Labs: blood glucose >300
mg/dL, ketones in blood
and urine, metabolic
acidosis
DM management
Nutritional therapy
Blood glucose monitoring
Medication
Exercise- 1 hr after meals,
snack to prevent
hypoglycemia
Insulin
Eye exam ever 5 years
after onset
15/15/15 rule!
Administer 15g of fast
acting card
Wait 15 min, recheck blood
glucose
Administer 15g more if
blood glucose remains less
than 70 mg/dL
Give 7g of protein when
blood glucose is within
normal limits
⦿ DKA (Diabetic
ketoacidosis): Life
threatening condition
w/bg >250 mg/dL &
Ketones in the
blood/urine,
metabolic acidosis.
S/S: hyperglycemia,
ketosis, acidosis,
dehydration [poor
skin turgor, dry
mucous membranes,
tachycardia,
orthostatic
hypotension),
lethargy and
weakness. Kussmaul’s
respirations, and
sweet fruity breath
odor
-Give D5 fluids, NS, and
regular insulin via IV
 CVD: MI & HTN
 Stroke
 Impaired vision
 Nerve damage,
leading to
neuropathic pain,
numbness, ischemia,
& infection.
 Hypoglycemia
 Hyperglycemia
 Kidney failure
 Problem w/ insulin

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