NSG 5003 WEEK 2 QUIZ: ADVANCED PATHOPHYSIOLOGY (20pages)

A hypersensitivity reaction that produces an allergic response is called: - Anaphylaxis The common hay fever allergy is expressed through a reaction that is mediated by which class of immunoglobulins? - IgE Which type of antibody is involved in type I hypersensitivity reaction? - IgE Blood transfusion reactions are an example of: - Alloimmunity During an IgE-mediated hypersensitivity reaction, which leukocyte is activated? - c. Eosinophils During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a result of which receptor action? - Histamine bound to H2 What characteristic do atopic individuals have that make them genetically predisposed to develop allergies? - c. Greater quantities of IgE What is the mechanism that results in type II hypersensitivity reactions? - d. Antibodies bind to the antigens on the cell surface. When mismatched blood is administered causing an ABO incompatibility, the erythrocytes are destroyed by - a. Complement-mediated cell lysis When antibodies are formed against red blood cell antigens of the Rh system, the blood cells are destroyed by: - Phagocytosis in the spleen When soluble antigens from infectious agents enter circulation, tissue damage is a result of: - d. Neutrophil granules and toxic oxygen products How are target cells destroyed in a type II hypersensitivity reaction? - d. Natural killer cells