NU 643 FINAL EXAM STUDY GUIDE AND UPDATED REGIS COLLEGE.

NU 643 FINAL EXAM STUDY GUIDE AND UPDATED REGIS COLLEGE. 

Inverse agonist binding
✔✔cause inactivation of signal transduction
A neurotransmitter binds to a receptor
✔✔causing electrical impulses to travel the neuron's axon; it eventually
releases the neurotransmitter and repeats the process with a postsynaptic
neuron, classical synaptic neurotransmission
True of pharmacokinetics
✔✔Accumulation of psychotropic drugs occurs faster in the brain than
adipose tissue
CYP450 TABLE
✔✔inhibitors and substrates INCREASE effectiveness of drug metabolized
inducers DECREASE effectiveness
Two main targets of signal transduction
✔✔gene expression and phosphoproteins
antagonist binding to receptor
✔✔unchanged signal transduction
first pass effect
✔✔metabolism of the drug in the liver, prior to reaching systemic
circulation