.png){kind=logo}
NU 643 FINAL EXAM STUDY GUIDE AND UPDATED REGIS COLLEGE.
Inverse agonist binding
âœâ€Ã¢Å“â€cause inactivation of signal transduction
A neurotransmitter binds to a receptor
âœâ€Ã¢Å“â€causing electrical impulses to travel the neuron's axon; it eventually
releases the neurotransmitter and repeats the process with a postsynaptic
neuron, classical synaptic neurotransmission
True of pharmacokinetics
âœâ€Ã¢Å“â€Accumulation of psychotropic drugs occurs faster in the brain than
adipose tissue
CYP450 TABLE
âœâ€Ã¢Å“â€inhibitors and substrates INCREASE effectiveness of drug metabolized
inducers DECREASE effectiveness
Two main targets of signal transduction
âœâ€Ã¢Å“â€gene expression and phosphoproteins
antagonist binding to receptor
âœâ€Ã¢Å“â€unchanged signal transduction
first pass effect
âœâ€Ã¢Å“â€metabolism of the drug in the liver, prior to reaching systemic
circulation
.png)