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1. Which medication is considered first-line treatment for a client
diagnosed with Major Depressive Disorder?
 A) Lithium
 B) Sertraline
 C) Risperidone
 D) Phenelzine
 Answer: B) Sertraline
 Rationale: Sertraline is an SSRI, which is commonly used as a first-line
treatment for depression due to its efficacy and relatively favorable side
effect profile.
2. A nurse is caring for a client with schizophrenia. Which antipsychotic
medication would require regular blood tests to monitor for
agranulocytosis?
 A) Aripiprazole
 B) Clozapine
 C) Olanzapine
 D) Quetiapine
 Answer: B) Clozapine
 Rationale: Clozapine can cause agranulocytosis, a potentially lifethreatening reduction in white blood cells, necessitating regular
monitoring of blood counts.
3. When educating a client about the use of mood stabilizers such as
lithium, what is an important aspect to emphasize regarding dietary
intake?
 A) Increase calcium-rich foods.
 B) Maintain consistent sodium intake.
 C) Avoid foods containing tyramine.
 D) Restrict fluid intake.
 Answer: B) Maintain consistent sodium intake.
 Rationale: Lithium levels can be affected by sodium intake; therefore,
clients should maintain a consistent level of sodium to prevent lithium
toxicity.
4. A client with Bipolar I Disorder is prescribed valproate. What is a
critical lab value to monitor?
 A) Liver function tests
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