NUR 170- Pharmacology Test 2-with 100% Verified Answers 2026/2027 (12pages)

A nursing student asks the nurse to explain the role of cyclooxygenase-2 (COX-2) and its role in inflammation. The nurse will explain that COX-2 Converts arachidonic acid into prostaglandins. Directly causes vasodilation and increased capillary permeability. Irritates the gastric mucosa to cause gastrointestinal upset. Inactivates bradykinins to cause inflammation and pain. A nursing student asks how nonsteroidal antiinflammatory drugs (NSAIDs) work to suppress inflammation and reduce pain. The nurse will explain that NSAIDs Exert direct actions to cause relaxation of smooth muscle. Inhibit cyclooxygenase that is necessary for prostaglandin synthesis. Interfere with neuronal pathways associated with prostaglandin action. Suppress prostaglandin activity by blocking tissue receptor sites. A patient who is taking aspirin for arthritis pain asks the nurse why it also causes gastrointestinal upset. The nurse understands that this is because aspirin Decreases gastrointestinal secretions. Increases hypersensitivity reactions. Inhibits both COX-1 and COX-2. Is an acid-base compound A patient is taking aspirin to help prevent myocardial infarction and is experiencing moderate gastrointestinal upset. The nurse will contact the patient’s provider to discuss changing from aspirin to which drug? A COX-2 inhibitor Celecoxib (Celebrex) Enteric-coated aspirin (Ecotrin) Nabumetone (Relafen) The nurse is performing a health history on a patient who has arthritis. The patient reports tinnitus. Suspecting a drug adverse effect, the nurse will ask the patient about which medication? Question 1 1 / 1 pts Question 2 1 / 1 pts Question 3 1 / 1 pts Question 4 1 / 1 pts Question 5 1 / 1 pts Aspirin (Bayer) Acetaminophen (Tylenol) Anakinra (Kineret) Prednisone (Deltasone) A patient who takes high-dose aspirin to treat rheumatoid arthritis has a serum salicylate level of 35 mg/dL. The nurse will perform which action? Assess the patient for tinnitus. Monitor the patient for signs of Reye’s syndrome. Notify the provider of severe aspirin toxicity. Request an order for an increased aspirin dose. The nurse is caring for a postoperative woman who is refusing opioid analgesics but is rating her pain as a 7 or 8 on a 10-point pain scale. The nurse will contact the provider to request an order for which analgesic medication? Diclofenac sodium (Voltaren) Ketoprofen (Orudis) Ketorolac (Toradol) Naproxyn (Naprosyn) A patient who has osteoarthritis with mild to moderate pain asks the nurse about taking over-thecounter ibuprofen (Motrin). What will the nurse tell this patient? “It may take several weeks to achieve therapeutic effects.” “Unlike aspirin, there is no increased risk of bleeding with ibuprofen.” “Take ibuprofen once daily for maximum analgesic benefit.” “Combine ibuprofen with acetaminophen for best effect.” The nurse is caring for a patient who has rheumatoid arthritis and who is receiving infliximab (Remicade) IV every 8 weeks. Which laboratory test will the nurse anticipate that this patient will need? Calcium level Complete blood count Electrolytes Potassium The nurse is teaching a patient about taking colchicine to treat gout. What information will the nurse include when teaching this patient about this drug? Question 6 1 / 1 pts Question 7 1 / 1 pts Question 8 1 / 1 pts Question 9 1 / 1 pts Question 10 1 / 1 pts Avoid all alcohol except beer. Include salmon in the diet. Increase fluid intake. Take on an empty stomach.