NUR 2115 Exam 1 Pharmacology
1. Medications used during mechanical ventilation fall into four categories
Answer
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sedatives, neuroleptics, analgesics, and paralytics
2. Sedatives include
Answer
benzodiazepines, barbituates, and propofol. These drugs decrease anxiety and produce amnesia,
but they don't relieve pain. Most of these drugs also have anticonvulsant effects without causing
cardiac depression. The exceptions to this are midazolam (Versed) and propofol (Diprivan),
which can cause cardiac depression.
3. The primary concerns related to use of sedatives during mechanical venti- lation are that
Answer
many have long half lives, and that drug levels can accumulate and cause prolonged effects in the
critically ill and elderly. This is particularily true of the barbituates, and may negatively impact
weaning attempts.
4. hasthe shortest half life of the benzodiazepines (1 hour), thus it isthe most commonly used.
Answer
Midazolam (Versed)
5. The other benefit to benzodiazepines is that their effects can be reversed with
Answer
flumazenil (Romazicon)
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