NUR 631 Neoplasia

NUR 631 Neoplasia
1. Cancer is associated with?
Answer
Altered expression of cellular genes that are re- sponsible for proliferation and differentiation
2. What characteristics of benign tumors can make them potentially lethal?
Answer
1. Proximity to criticalstructures (obstructing airway, growth in brain creating increased
intracranial pressure)
2. Some benign cells have shown potential to become malignant
3. Describe the common characteristics of benign tumors
Answer
1. Do not invade adjacent tissue
2. typically encapsulated
3. Resemble their tissue of origin (liver, skin)
4. is a lack of differentiated features in malignant cells.
What is this correlated with?
Answer
Anaplasia More aggressive tumors
5. What characteristic determines the diagnosis of malignancy?
Answer
Invasion of local tissue or metastasis to distant sites
6. The growth rate of tumors is typically slow whereas the growth rate of
tumors is rapid
Answer
Benign
Malignant