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1. Which of the following statements accurately describes
pharmacogenetics?
a) It refers to the study of how genetic differences influence
an individual's response to medications.
b) It involves the study of how the environment affects the
efficacy of medications.
c) It focuses on the development of new pharmaceutical
drugs based on genetic factors.
d) It investigates the side effects of medications on
different populations.
Answer: a) It refers to the study of how genetic differences
influence an individual's response to medications.
Rationale: Pharmacogenetics explores the genetic
variations that affect an individual's response to drugs,
allowing for personalized medicine based on genetic
makeup.
2. Cytochrome P450 enzymes are the most significant
enzymes involved in drug metabolism. Which of the
following CYP enzymes is responsible for metabolizing
approximately half of all medications?
a) CYP1A2
b) CYP2C9
c) CYP2D6
d) CYP3A4
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