NUR505 Advanced Pathophysiology LATEST MIDTERMS REVIEW QUESTIONS & ANSWERS

NUR505 Advanced Pathophysiology LATEST MIDTERMS REVIEW QUESTIONS & ANSWERS

1. A patient presents with a chronic cough and sputum
production, characteristic of chronic bronchitis. What
pathophysiological change primarily contributes to these
symptoms?
 - A) Hyperactivity of the immune response
 - B) Hypertrophy and hyperplasia of mucus-secreting glands
 - C) Reduction in surfactant production
 - D) Decreased alveolar elasticity
 Answer: B) Hypertrophy and hyperplasia of mucus-secreting
glands
 Rationale: Chronic bronchitis involves enlargement and
increased numbers of mucus glands, leading to excessive mucus
production.
2. Which genetic mutation is most commonly associated with
cystic fibrosis, affecting the CFTR protein?
 - A) Sickle cell mutation
 - B) ΔF508 deletion
 - C) BRCA1 mutation
 - D) MTHFR gene variation

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