NURS 215 FUNDAMENTALS OF NURSING LATEST UPDATED FINAL EXAM STUDY GUIDE ARIZONA COLLEGE OF NURSING

NURS 215 FUNDAMENTALS OF NURSING LATEST UPDATED FINAL EXAM STUDY GUIDE ARIZONA COLLEGE OF NURSING
Additional Pharmacokinetic Factors Specific to Children
✔✔Decreased gastric acid production and slower gastric emptying time
Decreased first-pass medication absorption due to immaturity of the liver
Increased absorption of topical medications (greater blood flow to the skin
and thinner skin)
High body water content (dilutes water-soluble medications)
Decreased protein-binding sites in the blood (until age 1 year), which can
result in an increase in the blood level of protein-binding medications
Physiologic Changes with Aging that Affect Pharmocokinetics
✔✔Increased gastric pH (alkaline)
Decreased gastrointestinal motility and gastric emptying time, resulting in
a slower rate of absorption
Decreased blood flow through the cardiovascular system, liver, kidneys
Decreased kidney function and glomerular filtration rate
Decreased protein-binding sites, resulting in l