ï‚· Question 1Â
1 out of 1 points
The culture and sensitivity testing of a patient's wound exudate indicates that a specificÂ
antibiotic is necessary for treatment. The United States Pharmacopeia–National FormularyÂ
indicates that the drug in question is 96% protein bound. What are the implications of thisÂ
fact?
ResponseÂ
Feedback:Â
A drug that is 96% protein bound has only 4% of ingested molecules free andÂ
active, a fact that is likely to necessitate a high dose of the drug. This doesÂ
not result in rapid absorption and/or excretion and does not indicate a needÂ
for increased protein intake.
ï‚· Question 2Â
1 out of 1 points
During a clinic visit, a patient complains of having frequent muscle cramps in her legs. TheÂ
nurse's assessment reveals that the patient has been taking over-the-counter laxatives for theÂ
past 7 years. The nurse informed the patient that prolonged use of laxatives
ResponseÂ
Feedback:Â
Long-term intake of laxatives, antidepressants, and antibiotics has been foundÂ
to deprive a person of most essential nutrients, such as vitamins. ProlongedÂ
use of laxatives is not known to turn urine acidic, cause urinary tractÂ
infections, counter the effect of other drugs, or inhibit the biotransformationÂ
of drugs.
ï‚· Question 3Â
1 out of 1 points
A patient with a recent diagnosis of acute renal failure has a long-standing seizure disorderÂ
which has been successfully controlled for several years with antiseizure medications. TheÂ
nurse should recognize that the patient's compromised renal function will likely
ResponseÂ
Feedback:Â
Impaired renal function will increase the half-life of drugs that areÂ
metabolized by the kidneys. This does not necessarily render suchÂ
medications ineffective and it does not decrease the first-pass effect. IVÂ
administration will not compensate for the patient's impaired renal function.
ï‚· Question 4Â
1 out of 1 points
A patient has been prescribed several drugs and fluids to be given intravenously. Before theÂ
nurse starts the intravenous administration, a priority assessment of the patient will be to noteÂ
the
ResponseÂ
Feedback:Â
Baseline body weight and height, heart rate, and blood pressure are allÂ
important considerations during the assessment of a patient. However, if aÂ
patient has to be given drugs intravenously, it is important to inspect the skinÂ
for rashes, moles, or sores, so those areas can be avoided as an insertion orÂ
injection site.
ï‚· Question 5Â
1 out of 1 points
A nurse is caring for a patient who has had part of her small intestine removed due to cancer.Â
She has also now developed hypertension and has been prescribed a new medication toÂ
decrease her blood pressure. While planning the patient's care, the nurse should consider aÂ
possible alteration in which of the following aspects of pharmacokinetics?
ResponseÂ
Feedback:Â
Because absorption takes place mostly in the small intestine, there could beÂ
possible alterations with this process. Distribution takes place in the bloodÂ
vessels; metabolism in the liver; and elimination via the kidneys. BecauseÂ
these systems are not affected by her surgery, these phases ofÂ
pharmacokinetics would not be altered.
ï‚· Question 6Â
1 out of 1 points
A patient who has been admitted to the hospital for a mastectomy has stated that she hasÂ
experienced adverse drug effects at various times during her life. Which of the followingÂ
strategies should the nurse prioritize in order to minimize the potential of adverse drug effectsÂ
during the patient's stay in the hospital?
ResponseÂ
Feedback:Â
In an effort to minimize the potential of adverse drug effects, it is necessaryÂ
to closely monitor the patient. It would be inappropriate for the nurse to alterÂ
the route or frequency of administration or to encourage herbal remedies thatÂ
also carry the potential for adverse effects.
ï‚· Question 7Â
1 out of 1 points
A home health nurse notes that there have been changes to a patient's oral drug regimen. TheÂ
nurse will closely monitor the new drug regimen to
ResponseÂ
Feedback:Â
Changes in the drug regimen may cause changes in drug absorption andÂ
thereby decrease the anticipated drug effect. This decrease is due to theÂ
prevention of binding and loss of absorption and overall drug effectiveness. AÂ
change in the drug regimen would not help a nurse to track the route ofÂ
metabolism or determine the speed of chelation. If any adverse effect were toÂ
occur as a result of a drug regimen change, it would not necessarily beÂ
immunotoxicity; it could also be nephrotoxicity, ototoxicity, or cardiotoxicity.
ï‚· Question 8Â
1 out of 1 points
A patient is treated with an antibiotic for an infection in his leg. After 2 days of taking theÂ
antibiotic, the patient calls the clinic and reports that he has a rash all over his body. TheÂ
nurse is aware that a rash can be an adverse effect of an antibiotic and can be either aÂ
biologic, chemical, or physiologic action of the drug, which is an example of
ResponseÂ
Feedback:Â
Pharmacodynamics is the biologic, chemical, and physiologic actions of aÂ
particular drug within the body and the study of how those actions occur,Â
including adverse effects. It is how the drug affects the body. TheÂ
pharmacodynamics of a drug is responsible for its therapeutic effects andÂ
sometimes its adverse effects. Pharmacotherapeutics refers to the desired,Â
therapeutic effect of the drug. Pharmacokinetics is the changes that occur toÂ
the drug while it is inside the body. Pharmacogenetics is the study of howÂ
genetic variables affect the pharmacodynamics of a drug in a specific patient.
ï‚· Question 9Â
1 out of 1 points
A patient has been prescribed 1 mg lorazepam (Ativan) sublingual prior to the scheduledÂ
insertion of a peripherally inserted central (PIC) line. How should the nurse direct the patientÂ
when administering this medication?
ResponseÂ
Feedback:Â
Sublingual tablets are placed under the tongue where they dissolve and areÂ
absorbed into the bloodstream. Swallowing the pill may render it lessÂ
effective, but is not unsafe. It is not recommended to chew and holdÂ
sublingual medications nor to hold them in the mouth for length of time