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Which of the following is a characteristic feature of acromegaly?
 a) Short stature
 b) Enlarged hands and feet
 c) Delayed puberty
 d) Hypoglycemia
 Correct Answer: b) Enlarged hands and feet
 Rationale: Patients with acromegaly often present with enlarged hands
and feet due to the overgrowth of bones and soft tissues.
What diagnostic test is commonly used to assess growth hormone levels in
patients suspected of having acromegaly?
 a) Thyroid function test
 b) Serum cortisol test
 c) Oral glucose tolerance test (OGTT)
 d) Insulin-like growth factor 1 (IGF-1) level
 Correct Answer: d) Insulin-like growth factor 1 (IGF-1) level
 Rationale: IGF-1 levels are a reliable indicator of growth hormone
excess and are commonly used in the diagnosis of acromegaly.
Which imaging modality is most commonly used to visualize pituitary
adenomas in patients with acromegaly?
 a) Magnetic resonance imaging (MRI)
 b) Computed tomography (CT) scan
 c) X-ray
 d) Positron emission tomography (PET) scan
 Correct Answer: a) Magnetic resonance imaging (MRI)
 Rationale: MRI is the preferred imaging modality for visualizing
pituitary adenomas due to its superior soft tissue contrast.
What is the first-line treatment for acromegaly?
 a) Surgical resection of the pituitary adenoma
 b) Radiation therapy
 c) Pharmacological therapy with somatostatin analogs
 d) Watchful waiting
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