ONS/ONCC Chemotherapy Immunotherapy Certification

ONS/ONCC Chemotherapy Immunotherapy Certification
Adaptive immunity leads to what? - ANS-immune system memory related to a pathogen or
foreign substance
Agranuloyctes are - ANS-T lymphocytes, B lymphocytes, monocytes
Granulocytes are - ANS-basophils, eosinophils, neutrophils
How are alkylating agents and platinum based chemo's different? - ANS-platinum based
chemo's do not have the molecule to to attach to and destroy DNA
How do alkylating agents function? - ANS-by causing a break in the DNA helix strand, causing
interference with DNA replication, which results in cell death
How to calculate an ANC - ANS-(%polys or segs + %bands) x WBC/100
If a mistake in copies of DNA occur next to a porto-oncogene, it can "turn on" and become
what? - ANS-oncogene
If innate immunity proves to be insufficient, what is mobilized? - ANS-adaptive immunity
Patient's with what diagnosis are more at risk for anaphylaxis to bleomycin? - ANS-lymphoma
The stem cell divides, producing undifferentiated stem cells that are of what lineage? -
ANS-myeloid or lymphoid
What are classes of antitumor antibiotics? - ANS-anthracyclines and non-anthracyclines
What are common plant alkaloids? - ANS-etoposide, docetaxol, paclitaxel, vinblastine,
vinorelbine
What are cytokines? - ANS-cytokines are secreted by lymphocytes with the intention of
stimulating macrophages and cytotoxic t lymphocytes to identify and kill pathogen infected cells
or tumor cells
What are examples of anthracyclines that? - ANS-doxorubicin, daunarubicin, epirubicin,
idarubicin
What are examples of non-anthracyclines? - ANS-actinomycin d, mitomycin c, bleomycin