PTX 301 Basics of Pharmacology & Toxicology Final Exam Guide Q & A 2026 (Complete And Verified Study material) (37pages) LEARNEXAMS

1. What is the primary mechanism of action for beta-blockers like propranolol in the treatment of hypertension? A. Vasodilation B. Beta-adrenergic antagonism C. Diuresis D. Calcium channel blockade Correct Answer: B Rationale: Beta-blockers work by blocking the effects of epinephrine (adrenaline) on the beta-adrenergic receptors, which reduces heart rate and cardiac output, leading to a decrease in blood pressure. 2. Which phase of drug metabolism is primarily responsible for the introduction of polar groups into the drug molecule? A. Phase I B. Phase II C. Phase III D. Phase IV Correct A