Quiz 1 Pharmacology 5334 Exam Questions & Answers Solutions.

Quiz 1 Pharmacology 5334 Exam Questions & Answers Solutions.
PCN drug-drug interactions - Answer - -aminoglycosides
-bacteriostatic antibiotics
-probenecid
Cephalosporin Generation 1 - Answer - -cephalexin
-cephazolin
-cephadoxil
Cephalosporin and PCN - Answer - Cross allergy w/PCN
Carbapenems - Answer - not active against MRSA
Vancomycin treats - Answer - gram positive
Vancomycin AE - Answer - ototoxicity, nephrotoxicity, red man syndrome
Vancomycin main danger - Answer - Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it increases
mortality
Monobactams treats - Answer - gram negative aerobic
Fosfomycin treats - Answer - enterococcus and Ecoli
Aminoglycosides treat - Answer - gram negative bacilli
Aminoglycosides adverse effects - Answer - ototoxicity and nephrotoxicity
aminoglycosides peak and trough - Answer - Peak: 30 min after IV or IM
Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like zero)
Sulfonamides MOA - Answer - inhibit folic acid synthesis
UTI drugs - Answer - 1) TMP/SMZ and nitrofurantoin
2) levofloxacin & ciprofloxacin