RN Relias Pharmacology Exam: Comprehensive Guide to the 2026 Assessment
The RN Relias Pharmacology Exam is a pivotal assessment designed to evaluate the proficiency of registered nurses in pharmacological principles and their application in clinical settings. As of 2026, the exam comprises 100 meticulously crafted questions, each accompanied by detailed, verified answers, ensuring a robust evaluation of a nurse's pharmacological acumen.
Structure and Content of the Exam
The exam is structured to encompass a broad spectrum of pharmacological topics, including:
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Pharmacokinetics and Pharmacodynamics: Understanding the absorption, distribution, metabolism, and excretion of drugs, alongside their physiological effects.
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Drug Classifications and Mechanisms of Action: In-depth knowledge of various drug classes and their specific mechanisms.
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Therapeutic and Adverse Effects: Identifying desired therapeutic outcomes and potential adverse reactions.
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Dosage Calculations and Administration: Competence in calculating accurate dosages and administering medications safely.
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Patient Education and Safety: Emphasizing the importance of educating patients on medication usage and ensuring safety protocols are followed.
Sample Questions and Detailed Answers
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Which of the following is considered an antiplatelet medication?
- A) Clopidogrel (Plavix)
- B) Warfarin (Coumadin)
- C) Heparin
- D) Enoxaparin (Lovenox)
Correct Answer: A) Clopidogrel (Plavix)
Rationale: Clopidogrel is an antiplatelet agent that inhibits platelet aggregation, thereby reducing the risk of thrombotic events.
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A 250mg dose of an oral medication has been ordered. The medication is supplied only in 100mg tablets. How many tablets would you administer?
- A) 2 tablets
- B) 2.5 tablets
- C) 3 tablets
- D) 3.5 tablets
Correct Answer: B) 2.5 tablets
Rationale: To achieve a 250mg dose, administering 2.5 tablets of 100mg each is necessary.
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Which medication is a leukotriene receptor antagonist?
- A) Montelukast (Singulair)
- B) Albuterol (Ventolin)
- C) Fluticasone (Flovent)
- D) Salmeterol (Serevent)
Correct Answer: A) Montelukast (Singulair)
Rationale: Montelukast is a leukotriene receptor antagonist used in the management of asthma and allergic rhinitis.
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What is the primary cause of Red Man Syndrome during vancomycin administration?
- A) Increased histamine production
- B) Bacterial endotoxin release
- C) Direct mast cell degranulation
- D) Rapid infusion rate
Correct Answer: A) Increased histamine production
Rationale: Red Man Syndrome is primarily due to increased histamine release, often exacerbated by rapid infusion rates.
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Which statement made by a person regarding hydrochlorothiazide (HCTZ) is correct?
- A) "I should take extra care when standing up or changing positions."
- B) "I can take this medication with any food."
- C) "This medication will increase my potassium levels."
- D) "I should avoid drinking fluids while on this medication."
Correct Answer: A) "I should take extra care when standing up or changing positions."
Rationale: Hydrochlorothiazide can cause orthostatic hypotension; patients should be advised to change positions slowly.
Study Resources
For comprehensive preparation, the following resources are recommended:
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RN Pharmacology A Relias Flashcards: An extensive set of flashcards covering key pharmacological concepts.
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Relias RN Pharmacology Test A Actual Exam with Questions and Answers: A compilation of actual exam questions with detailed answers.
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Prophecy Relias Pharmacology RN A Latest 2026 Actual Exam 100 Questions and Correct Detailed Answers with Rationales: A resource offering 100 questions with rationales, aiding in understanding the reasoning behind each answer.
Preparation Tips
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Understand the Exam Format: Familiarize yourself with the structure and types of questions to anticipate during the exam.
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Review Rationales: Focus on understanding the reasoning behind each answer to enhance critical thinking skills.
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Practice Dosage Calculations: Regularly practice dosage calculations to ensure accuracy in clinical settings.
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Stay Updated: Keep abreast of the latest pharmacological guidelines and drug information.
Conclusion
The RN Relias Pharmacology Exam serves as a comprehensive assessment of a nurse's pharmacological knowledge and clinical application skills. Thorough preparation using the recommended resources and study strategies will equip candidates to excel in the 2026 examination.
Below are sample Questions and Answers:
Which of the following would be used as part of the preop
procedure to prevent infection? - ANSWER-Prophylactic
antibiotics
Two days after surgery, your 72-year-old patient is showing
signs of agitation and confusion, which is not his baseline. The
severity fluctuates throughout the day. His medications include
hydromorphone (Dilaudid), amlodipine (Norvasc), alprazolam
(Xanax), and carbidopa-levodopa (Sinemet). What condition do
you MOST likely suspect? - ANSWER-Delirium
What is the proper technique when suctioning a tracheostomy? -
ANSWER-Suction in a circular motion while the catheter is
being pulled out.