UC 8024 PHARM EXAM 4 QUESTION AND ANSWERS CORRECTLY SOLVED
Question : Biguanides (Metformin)
Correct answer: First line agent for DMII
MOA: Decreases liver glucose production
ADE: diarrhea and abdominal pain
BBW: Lactic Acidosis - rare
Contra: Pts with renal impairment
Question : Sulfonylureas
Correct answer: MOA: Increased endogenous insulin secretion
(binding to pancreatic beta receptors to trigger insulin release)
ADE: Hypoglycemia (combined w/ other agents), wt gain, rash
(sulfa), HA, N/V, photosensitivity
Caution: Renal/hepatic impairment
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