UNE MED BIOCHEM UNIT 3 TEST QUESTIONS WITH ACCURATE ANSWERS A+
An increase in the ratio of insulin to glucagon will increase the activity of which of the following enzymes
(+ indicates activity is increased; - indicates activity is not increased by insulin)? - ANS-(-) hormone
sensisitve lipase
(+) acetyl-CoA carboxylase
(+PFK2)
(+) Gycogen synthase
when insulin is elevated fed state pathways will be persistent. This will include the activation of acetylCoA carboxylase will be activated in fatty acid synthesis. PFK2 in gycolysis (breakdown of glucose) and
glycogen synthase will also be active converting excess glucose to glycogen to be stores for later.
hormone sensitive lipase is active in lipolysis --> in the fasting state
Which of the following is the regulatory enzyme for fatty acid synthesis?
Citrate lyase
Malic enzyme
Fatty acid synthase
Acetyl-CoA carboxylase - ANS-Acetyl-CoA carboxylase
the regulatory step in fatty acid syntehsis is the synthesis of malonyl-coA by acetyl-CoA carboxylase. This
reaction uses CO2 and bioton to add carbon to cystolic acteyl-COA
Fatty Acid synthase is used in Beta oxidation!
Insulin stimulates lipogenesis through several mechanisms. Which of the following is not an insulin
stimulated process that enhances lipogenesis?
Decreased activity of the pyruvate dehydrogenase complex
Decreased levels of cAMP
Increased glucose transport into the cells
Increased activity of acetyl-CoA carboxylase - ANS-Decreased activity of the pyruvate dehydrogenase
complex
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