WGU D027 NURS 5204 Advanced Pathopharmacological Foundations COMPREHENSIVE FA EXAM QUESTIONS & ANSWERS
1. A patient with chronic heart failure is prescribed Digoxin.
Which mechanism of action is primarily responsible for its
therapeutic effect?
- A) Inhibition of angiotensin-converting enzyme
- B) Blockade of beta-adrenergic receptors
- C) Inhibition of sodium-potassium ATPase
- D) Stimulation of nitric oxide release
Answer: C) Inhibition of sodium-potassium ATPase
Rationale: Digoxin works by inhibiting the sodiumpotassium ATPase pump, leading to an increase in
intracellular calcium and enhanced cardiac contractility.
2. In managing Parkinson's disease, the rationale for using
Levodopa is that it:
- A) Decreases acetylcholine levels
- B) Increases dopamine levels in the brain
- C) Prevents oxidative stress in neurons
- D) Blocks NMDA receptors
Answer: B) Increases dopamine levels in the brain
Rationale: Levodopa acts as a precursor to dopamine,
thereby increasing dopamine levels and improving
symptoms in Parkinsonian patients.
3. Which of the following antihypertensive agents is most
likely to cause a persistent dry cough as a side effect?
- A) Losartan
- B) Lisinopril
- C) Amlodipine
- D) Hydrochlorothiazide
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