1. Hydrochlorothiazide Microzide, a thiazide diuretic, is metabolized:

3P Urology

1. Hydrochlorothiazide (Microzide), a thiazide diuretic, is metabolized:

Answer: minimally.

2. An adverse reaction associated with loop diuretics is:

Answer: hypokalemia.

3. Nitrofurantoin (Macrobid) should NOT be administered to a patient who:

Answer: -has a CrCl <30 ml/min.

4. Desmopressin acetate (DDAVP), used to treat nocturnal enuresis,:

Answer: increases water reabsorption in the renal collecting ducts and results in an increased urineosmolality.

• The drug of choice for blood pressure control in patients with renal insufficiency is:

Answer: angiotensin-converting enzyme inhibitors.

• Which of the following treatments for urinary incontinence is NOT an anti-cholinergic?

Answer: Doxazosin (Cardura)

7. Oxybutynin (Ditropan), used in the treatment of cystitis,:

Answer: decreases urgency.

• A 48-year-old patient with diabetes, hypertension, and renal insufficiency is taking an

angiotensin receptor blocker (ARB). ARBs act by:

Answer: inhibiting the binding of angiotensin II to angiotensin I receptor sites on vascular smooth muscles.

9. Nitrofurantoin (Macrobid), an antimicrobial, is NOT active against:

Answer: -Pseudomonas aeruginosa.

• Patients should be informed that oxybutynin (Ditropan) used in the treatment of

overactive bladder, may cause:

Answer: edema of the laryngopharynx.

• When using ciprofloxacin (Cipro) for the treatment of urinary tract infections (UTIs), the

patient should be monitored for:

Answer: tendinitis and tendon rupture.

• In the case of non-gonococcal urethritis, the patient should be treatedwith:

Answer: azithromycin (Zithromax) 1 gram orally. 1 / 2

13. Finasteride (Proscar):

Answer: is unsafe if handled during pregnancy and lactation.

14. Patients taking mirabegron (Myrbetriq) should be monitored for:

Answer: hypertension.

• Which of the following is a beta 3 adrenergic agonist used in the treatmentof overactive

bladder?

Answer: Mirabegron (Myrbetriq)

• Patients receiving imipramine (Tofranil) for the treatment of nocturnalenuresis should be

advised to:

Answer: use sunscreen when outdoors.

17. Fluoroquinolones are associated with:

Answer: tendinitis and hypoglycemia.

• Initial and routine monitoring for patients who are receiving tamsulosin(Flomax) should

include:

Answer: prostate-specific antigen.

19. Thiazide diuretics are contraindicated in patients who have:

Answer: a hypersensitivity to sulfonamides.

• The recommended treatment option for uncomplicated urinary tract infections (UTIs) in

children between the ages of 2 and 13 who have an allergy to cephalosporin is:

Answer: Trimethoprim/sulfamethoxazole (Bactrim)

• The brand name of imipramine, used in the treatment of nocturnal enuresis, is:

Answer: Tofranil.

• Oxybutynin (Ditropan), used in the treatment of dysuria, is classified asan:

Answer: anti-spasmodic agent.

• Cefixime (Suprax) used for treatment of urinary tract infections (UTIs) isa:

Answer: third-generation cephalosporin.

24. In the treatment of urinary tract infections (UTIs), sulfa agents:

Answer: block thesynthesis of folic acid by bacteria and inhibit replication.

• A 23-year-old patient with an uncomplicated urinary tract infection (UTI) is allergic to

sulfamethoxazole/trimethoprim (Bactrim).This patient should betreated with:

Answer: Cipro.

• / 2