AANP FNP Exam | / Latest Edition Actual Family Nurse Practitioner Board Exam | 150 Verified Questions with Correct, Detailed Answers | A+ Grade Introduction This complete resource includes 150 verified multiple-choice questions from the AANP Family Nurse Practitioner (FNP) certification exam. All questions are based on real exam content and have been updated to match the most current clinical standards and board expectations. Designed to ensure readiness for the national certification exam with detailed explanations to support clinical decision-making.Answer Format All correct answers are clearly marked in bold and green to enable fast, accurate review.Each question includes detailed rationales to reinforce understanding of core concepts and evidence-based practice.Question 1 A 28-year-old woman presents with petechiae, easy bruising, and a platelet count of 12,000/mm³. She has no significant medical history and is not taking any medications.Physical examination reveals no other abnormalities. What is the most appropriate initial diagnostic test for this patient?
- Bone marrow aspiration
- HIV and HCV testing
- Peripheral blood smear
- Review of dietary history
- Gently pull the outer ear up and back with the free hand.
- Gently pull the outer ear down and back with the free hand.
- Move the otoscope 1 to 2 cm forward before looking into it.
- Insert the viewing piece of the otoscope several centimeters into the ear canal.
Rationale: A peripheral blood smear is the most appropriate initial test to evaluate thrombocytopenia, as it assesses platelet morphology and rules out pseudothrombocytopenia (e.g., platelet clumping). Bone marrow aspiration is invasive and not first-line. HIV/HCV testing is relevant but not initial, and dietary history is less likely to explain severe thrombocytopenia.Question 2 A nurse practitioner performs an otoscopic examination on a middle adult patient’s right ear.What is the correct technique for improving visualization of the ear canal during the examination?
Rationale: For adults, gently pulling the outer ear up and back straightens the ear canal for 1 / 4
better visualization during an otoscopic exam. Pulling down and back is used for children.Deep insertion or moving the otoscope forward without visualization risks injury.Question 3 Which finding during a skin cancer screening of an adult male with a history of outdoor occupation and minimal sun protection should the nurse practitioner be most vigilant for?
- Multiple comedones on the nose and forehead
- Diffuse erythema and scaling on the trunk and extremities
- Small, pearly papule with central ulceration and rolled elevated edges
- A firm, brownish nodule on the left leg that dimples when pinched
- Amoxicillin 500 mg TID for 7 days
- Azithromycin 500 mg on day 1, then 250 mg daily for 4 days
- Levofloxacin 750 mg daily for 7 days
- Doxycycline 100 mg BID for 10 days
- Order pelvic ultrasound
- Prescribe oral contraceptives
- Educate on normal menstrual variation and monitor
- Refer to gynecology
Rationale: A pearly papule with central ulceration and rolled edges is characteristic of basal cell carcinoma, common in sun-exposed individuals. Comedones suggest acne, diffuse erythema may indicate dermatitis, and a dimpling nodule suggests a benign lesion like a dermatofibroma.Question 4 A 45-year-old woman with type 2 diabetes presents with a productive cough and fever for 3 days. Chest X-ray shows a right lower lobe infiltrate. What is the most appropriate initial treatment?
Rationale: Azithromycin is a first-line treatment for community-acquired pneumonia (CAP) in outpatient settings, covering common pathogens like Streptococcus pneumoniae and atypical organisms. Amoxicillin does not cover atypicals, and levofloxacin is reserved for complicated cases or resistance. Doxycycline is an alternative but not first-line.Question 5 A 16-year-old female presents for a routine check-up and reports irregular menses. She is not sexually active and has no other symptoms. What is the most appropriate initial management?
Rationale: Irregular menses in adolescents are common due to anovulatory cycles in the first few years post-menarche. Education and monitoring are appropriate initially unless symptoms suggest pathology (e.g., PCOS). Ultrasound, contraceptives, or referral are not indicated without further evaluation.Question 6 2 / 4
A 60-year-old male with hypertension presents with a blood pressure of 160/90 mmHg. He is on lisinopril 20 mg daily. What is the most appropriate next step?
- Continue current dose and recheck in 6 months
- Add hydrochlorothiazide 12.5 mg daily
- Switch to losartan 50 mg daily
- Increase lisinopril to 40 mg daily
- Azithromycin 10 mg/kg/day for 5 days
- Amoxicillin 50 mg/kg/day for 10 days
- Cephalexin 25 mg/kg/day for 7 days
- Clindamycin 7 mg/kg/day for 10 days
- Start levothyroxine
- Refer to endocrinology
- Order thyroid ultrasound
- Monitor without intervention
- Annual chest X-ray
- Mammography every 1–2 years
- PSA screening 3 / 4
Rationale: For uncontrolled hypertension, adding a second agent like hydrochlorothiazide (a thiazide diuretic) is recommended to achieve BP goals (<140/90 mmHg). Increasing lisinopril or switching to losartan may be considered later, and continuing without adjustment is inadequate.Question 7 A 6-year-old child presents with a sore throat, fever, and tonsillar exudate. Rapid strep test is positive. What is the most appropriate treatment?
Rationale: Amoxicillin is the first-line treatment for streptococcal pharyngitis in children due to efficacy, safety, and cost. Azithromycin is an alternative for penicillin allergy, and cephalexin or clindamycin are not first-line.Question 8 A 32-year-old pregnant woman at 16 weeks gestation reports fatigue and palpitations.Thyroid function tests show TSH 0.1 mIU/L and elevated free T4. What is the most appropriate next step?
Rationale: Hyperthyroidism in pregnancy (likely Graves’ disease) requires specialist management due to risks to the fetus and mother. Referral to endocrinology is appropriate.Levothyroxine treats hypothyroidism, ultrasound is not initial, and monitoring alone risks complications.Question 9 Which of the following is a key component of health promotion for a 50-year-old female patient?
- Routine ECG
- Start oral prednisone
- Albuterol nebulizer and antibiotics
- Order chest CT
- Admit to hospital
Rationale: Mammography every 1–2 years is recommended for breast cancer screening in women aged 50–74, per USPSTF guidelines. Chest X-rays and ECGs are not routine for asymptomatic patients, and PSA screening is for prostate cancer (males).Question 10 A 70-year-old male with COPD presents with increased dyspnea and sputum production.Physical exam shows wheezing and oxygen saturation of 90%. What is the most appropriate initial management?
Rationale: Acute COPD exacerbation is managed with albuterol (short-acting
bronchodilator) and antibiotics (e.g., azithromycin) for suspected bacterial infection.Prednisone may be added, but bronchodilation is first-line. CT is not initial, and admission depends on severity.Question 11 A 3-month-old infant presents with fever, poor feeding, and lethargy. What is the most appropriate initial action?
- Administer acetaminophen and monitor at home
- Admit to hospital for sepsis evaluation
- Order outpatient blood work
- Prescribe oral antibiotics
- Contact dermatitis
- Lyme disease
- Psoriasis
- Tinea corporis
- / 4
Rationale: Fever and lethargy in a 3-month-old suggest possible serious bacterial infection (e.g., sepsis). Hospital admission for a full sepsis workup (blood culture, lumbar puncture, etc.) is critical due to the infant’s age and risk. Outpatient management or antibiotics without evaluation is unsafe.Question 12 A 22-year-old male presents with a painful, erythematous rash on his trunk that started after a hiking trip. The rash is annular with central clearing. What is the most likely diagnosis?
Rationale: An annular rash with central clearing (erythema migrans) after outdoor exposure is characteristic of Lyme disease, caused by Borrelia burgdorferi. Contact dermatitis is typically pruritic, psoriasis presents with silvery scales, and tinea has scaling edges.