AMNH GENETIC AND GENOMIC IN NURSINGACTUAL

AMNH GENETIC AND GENOMIC IN NURSING(ACTUAL

/ EXAM QUESTIONS AND VERIFIED CORRECT

ANSWER GRADED A+

A 40 yr old man has a mom dx with breats CA at age 45, a dad dx smoking related lung CA at age 55, 33 yr old sister with breast CA and 38 yr old sister with ovarian cancer, ask if he should be concerned for his cancer risk. What is the best response -----Answers----Your risk for breast CA may be increased and required nor investigation, however, your risk for lung cancer is not affected by this history

Julia age 32 is BRCA1 +, which is known to greatly increase the risk for breast and ovarian CA. She was tested because her mom who had ovarian CA was BRCA1 + . Julia has decided to have both her ovaries removed because she believes that in her family, being BRCA1+ increases the risk for ovarian CA only. How should a genetic counselor respond -----Answers- ---Clarify that a BRCA1 mutation does not preferentially express ovarian CA over breast CAin any given family

What statement regardignn general cancer development is true -----Answers----The risk for CA development increase with age

Why is determining the genetic contribution important to assess in stroke pt -----Answers----Stroke calcification and phenotype remain heterogeneous 1 / 2

What tissue is most likely to provide an adequate DNA sample for genetic testing -----Answers----Nasal epithelial cells

A pt whose mom has huntington's disease is considering genetic testing but is not sure whether she really wants to know if she has the mutation. She asks you why you would do if your mom had the disease -----Answers----I can only tell you the benefits and the risk of testing, you must make this decision yourself

Why are people who have poor DNA repair mechanism at greater risk for CA development -----Answers----Their somatic mutations are more likely to be permanent

Which statement best describes the role of tumor suppressor genes in CA development -----Answers----Tumor suppressor genes control or modify the activity of oncogenes, reducing the risk for CA development

A pt 34 yrs old is concerned about being HNPCC carrier, cause his dad died of colon CA at age 39, his dad sister died of colon CA at age 41, and brother age 37 now has colon cancer. the brother's testing is negative for all the known mutation associated with inherited forms of colon cancer. How should the pt be counseled another his risk of colon CA ----- Answers----Explain that testing for him would e of no benefits because of the current test limitation by that his family history does place him a high risk.Lethal cardiac arrhythmia with long QT -----Answers----Torsade de Pointes

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