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Anti-Parkinson’s Drugs
By: Muhammad Aurangzeb
Lecturer-INS/KMU
Objectives
By the completion of this section the learners will be able to:
•Describe the action of anticholinergic drugs and dopaminergic drugs in treatment of Parkinsonism.•Differentiate between the types of commonly used anti- Parkinson’s drugs.•Describe the side effects of anti-Parkinson drugs.•Discuss the nursing interventions including clients teaching of drugs used in the treatment of Parkinson’s disease •Calculate the drug dosage accurately for oral and parental anti Parkinson’s drugs
Parkinsonism •Parkinsonism is a progressive neurological disorder of muscle movement, characterized by –tremors, –muscular rigidity, –bradykinesia (slowness in initiating and carrying out voluntary movements), –and postural and gait abnormalities.
Parkinson Disease •It is a Extrapyramidal motor disorder occurs due to degeneration of dopaminergic neurons in the substantia nigra pars compacta (SN-PC) result in dopamine deficiency •It occur in 2% elderly population •Classically disease of 7th decade of life •An imbalance between dopaminergic(inhibitory neuron) and excitatory cholinergic neuron Cholinergic over activity
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