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BIOL303 EXAM 3 ACKERSON PT 2 NEWEST ACTUAL /
QUESTIONS AND ANSWERS VERIFIED/GRADED A+
dna methylation - ----Answers----1) before replication dna is methylated at CpG dinucleotides 2) during replication new dna strand has no methyl groups 3) methyl groups on the old strand attract methyltransferase enzymes, add methyl groups to unmethylated strand
bee methylation - ----Answers----royal jelly suppresses Dnmt3, which methylates dna, leading to expression of genes that encode characteristics of queen
how many and what posttranslational modifications occur in histone proteins - ----Answers----over 100
phophates, methyl groups, acetyl groups, ubiquitin
maintenance of histone modifications are passed to daughter cells
open config vs closed config - ----Answers----open:
unmethylated and histones acetylated, transcribably
closed: methylated at CpG islands and histones are
deacetylated, cannot transcribe 1 / 2
epigenetic effects of RNA molecules - ----Answers---- formation of heterochromatin histone modifications site specific dna methylation gene splicing epigenetic regulatory networks
miRNAs and siRNAs lncRNA
paramutation - ----Answers----interaction between two alleles that leads to a heritable change in expression of one of the alleles
epialleles - ----Answers----genetically identical but produce heritable differences in phenotype through epigenetic processes
development of x-inactivation - ----Answers----Xa and Xi chromosomes have Xist gene
Xist gene on Xi transcribed into an lncRNA and coats Xi but not Xa
Xist RNA recruits PRC2, produces histone modifications on Xi
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