CHEMOTHERAPY AND BIOTHERAPY GUIDELINES - ONS 942P

CHEMOTHERAPY AND BIOTHERAPY GUIDELINES - ONS 942P

NEWEST ACTUAL / EXAM WITH QUESTIONS AND

VERIFIED CORRECT ANSWERS.

Adriamycin/Doxorubicin - -----Answers---vesicant, red urine/sweat, N/V, alopecia, nail changes/sensitivity, myelosuppression, anorexia, cardiotoxic - ECHO q12 weeks, watch EF change from baseline chew ice during administration to reduce mucositis

Alimta Permetrexed - -----Answers---lung, mesothelioma (asbestos) 10m infusion, q3 weeks depletes B12 and folic acid PO folic acid daily, q9 week B12 injection and 1 week prior to infusion 4mg oral steroid day prior, of and after infusion N/V, diarrhea, mucositis, rash - use steroids

Leucovorin - -----Answers---closely related to folic acid head and neck, colorectal used to help 5-FU and also protects normal cells in bone marrow and digestive tract from chemotherapy agents

Leuprolide Eligard 1 / 2

Lupron - -----Answers---hormone antagonist prostate, uterine fibroids, endometriosis stops the release of testosterone and estrogen subsequently slows cancer cells that rely on these hormones ice or spray prior for large bore needle

Navelbine Vinorelbine - -----Answers---plant alkaloid - vinca lung, breast N/V,constipation, peripheral neuropathy, fatigue, weakness

Neulasta Pegfilgrastim - -----Answers---granulocyte-colony stimulating factor leukopenia stimulates bone marrow to make more neutrophils one injection per cycle of chemo can cause bone marrow ache

• hips, femur, occiput
• take tylenol

Rare: spleen enlargement - swelling left side under ribs, pain

left shoulder, very low WBC or sepsis 1st injection, stay for 20m, watch for hives, rash, facial edema, NV, ARDS, anaphylaxis

Mucositis - -----Answers---Inflammation, sloughing and ulceration of G.I. system, specifically oral mucosa. Susceptible

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