EVOLVE HESI PHARMACOLOGY VERSION 1

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Evolve Hesi Pharm Actual Exam Version 1,2,3 And

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EVOLVE HESI PHARMACOLOGY VERSION 1

Which class of antineoplastic chemotherapy agents resembles the essential elements required for DNA and RNA synthesis and inhibits enzymes necessary for cellular function and replication?

• Alkylating agents
• Antimetabolites
• Antitumor antibiotics
• Plant alkaloids - CORRECT ANSWER -B. Antimetabolites

Rationale; Antimetabolites exert their action by inhibiting the enzymes necessary for cellular function and replication. Options A, C, and D have a different mechanism of action.

A child with cystic fibrosis is receiving ticarcillin disodium for Pseudomonas pneumonia. For which adverse effect should the nurse assess and report promptly to the health care provider? 1 / 4

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• Petechiae
• Tinnitus
• Oliguria
• Hypertension - CORRECT ANSWER -A. Petechiae

Rationale; Adverse effects of ticarcillin disodium include hypothrombinemia and decreased platelet adhesion, which can result in the presence of petechiae. Options B, C, and D are not adverse effects primarily associated with the administration of ticarcillin disodium.

A male client with prostatic carcinoma has arrived for his scheduled dose of docetaxel chemotherapy. What symptom would indicate a need for an immediate response by the nurse prior to implementing another dose of this chemotherapeutic agent?

• A cough that is new and persistent
• Persistent nausea and vomiting
• Fingernail and toenail changes 2 / 4

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• Increasing weakness and neuropathy - CORRECT ANSWER -A. A

cough that is new and persistent

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Rationale; Option A is an adverse effect that is immediately life threatening. Severe fluid retention can cause pleural effusion (requiring urgent drainage), dyspnea at rest, cardiac tamponade, or pronounced abdominal distention (caused by ascites). Options B, C, and D are all adverse effects from chemotherapy and need to be monitored consistently.

A 26-year-old primigravida client is experiencing increasing discomfort and anxiety during the active phase of labor. She requests something for pain. Which analgesic should the nurse anticipate administering?

• Butorphanol
• Hydromorphone
• Morphine sulfate
• Codeine sulfate - CORRECT ANSWER -A. Butorphanol

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Rationale; Butorphanol is a mixed agonist-antagonist analgesic resulting in good analgesia but with less respiratory depression, nausea, and vomiting compared with opioid agonist analgesics.

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Which question should the nurse ask a client prior to the initiation of treatment with IV infusions of gentamicin sulfate?

• "Are you having difficulty hearing?"
• "Have you ever been diagnosed with cancer?"
• "Do you have any type of diabetes mellitus?"
• "Have you ever had anemia?" - CORRECT ANSWER -A. "Are you

having difficulty hearing?"

Rationale; Complications of gentamicin sulfate therapy include ototoxicity, nephrotoxicity, and neurotoxicity. Determining if the client is hard of hearing prior to initiation of this aminoglycoside will be helpful as the treatment progresses and ototoxicity is identified as a possible complication. Options B, C, and D are important elements of any medical history, but they do not have the priority of option A when assessing for complications of aminoglycoside therapy.

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