Exam 1 Module 1: NUR 2474

Exam 1 Module 1: NUR 2474 /

NUR2474 (Latest Update 2025 / 2026) Pharmacology for Professional Nursing | Questions & Answers | 100% Correct | Grade A - Rasmussen

Question:

What is the ED50?

Answer:

The effective dose required to produce a therapeutic response in 50% of the population.

Question:

What is the therapeutic index?

Answer:

A measure of drug safety; the ratio of a drug's LD50 (lethal dose) to its ED50 (effective dose).

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Question:

Why is a higher therapeutic index safer?

Answer:

A larger difference between the LD50 and ED50 means the drug is safer because the toxic and effective doses are further apart.

Question:

What are drug-drug interactions?

Answer:

Interactions that occur when a patient takes more than one drug, leading to intensification, reduction, or a unique response.

Question:

How can drug interactions intensify effects?

Answer:

Drug interactions can intensify therapeutic or adverse effects, such as aspirin and warfarin increasing bleeding risk.

Question:

How can drug interactions reduce effects?

Answer:

Interactions can reduce therapeutic or adverse effects, such as naloxone reducing the effects of a morphine overdose. 2 / 4

Question:

What is a direct chemical or physical interaction in drug interactions?

Answer:

Drugs interacting with each other in solution, which is why IV drugs should not be combined without compatibility testing.

Question:

What is the cytochrome P450 system?

Answer:

A group of enzymes responsible for the metabolism of many drugs; it can be induced or inhibited by certain drugs.

Question:

What effect does grapefruit juice have on drug metabolism?

Answer:

It inhibits the metabolism of certain drugs, raising their blood levels and increasing the risk of toxicity.

Question:

How can food affect drug absorption?

Answer:

Food can either increase or decrease drug absorption, depending on the type of food and drug combination. 3 / 4

Question:

What effect does Vitamin K have on warfarin?

Answer:

Vitamin K reverses the effects of warfarin, reducing its anticoagulant effects.

Question:

Why is it important to monitor herbal supplement interactions?

Answer:

Herbal supplements, like St. John's Wort, can induce drug-metabolizing enzymes and reduce blood levels of medications.

Question:

What is the impact of combining MAOIs with tyramine-containing foods?

Answer:

It can lead to high blood pressure and increased risk of toxicity due to the interaction with tyramine.

Question:

What should you be cautious of when using potassium-sparing diuretics and salt substitutes?

Answer:

The combination can lead to high potassium levels, which can be dangerous.

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