Exam 1: NU664B NU 664B Latest

Exam 1: NU664B / NU 664B (Latest

Update 2025 / 2026) Primary Care of Family I | Questions & Answers | Grade A | 100% Correct - Regis

Question:

weight loss in HTN

Answer:

systolic BP down 1mm for every pound lost in obese persons

Question:

How do thiazide diuretics work?

Answer:

• Reduce reabsorption of sodium and chloride in ascending loop of Henle &

early distal tubules.

• decrease peripheral resistance
• drug of choice for patients with NO comorbidities, black persons, obese,

and elderly

• favorable in osteopenia (helps keep Ca in body)
• / 4

Question:

AsVCD score

Answer:

• age

-race

• Blood pressure
• total cholesterol
• HDL & LDL
• any medication treatments
• DM?

-smoking

Question:

what is the max effective dose of HCTZ?

Answer:

25 mg daily

• / 4

Question:

ACE drugs

Answer:

-pril drugs

first line for:

1. HF

• LV dysfunction

3. DM

• Proteinuric kidney disease

NOT for breastfeeding or pregnant women

Question:

side effects of ACE-I and how to manage

Answer:

• angioedema - more common in blacks, if this happens, drug should be

stopped. patient should also NOT try ARB

• cough - more common in blacks and women, can switch to an ARB
• hyperkalemia
• renal insufficiency - check baseline creatinine before starting)
• hypotension - restart at half dose 3 / 4

Question:

ARB drugs

Answer:

-sartan drugs

• good for pts who don't tolerate ACE-I's
• don't give w an ACE
• peak effect = 4-6 weeks

Question:

calcium channel blockers

Answer:

agents that inhibit the entry of calcium ions into heart muscle cells, causing a slowing of the heart rate, a lessening of the demand for oxygen and nutrients, and a relaxing of the smooth muscle cells of the blood vessels to cause dilation; used to prevent or treat angina pectoris, some arrhythmias, and hypertension

- adverse effect: peripheral edema - most common in women, dose > 5mg

• adding an ACE decreases risk of edema

two types:

dyhydropyridines (work more peripherally) = amlodipine

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