PSYCHIATRY EOR
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What's the common genetic heritability that is shared with this condition? - ANSWER-Generalized anxiety disorder [GAD]
1st line: SSRIs [sertraline, paroxetine]
2nd line: Benzos [Lorazepam]
Usually starts: early adulthood in women
Genetic heritability with: Major Depressive Disorder
Pt presents with:
- frequent episodes of palpitations
- diaphoresis, feeling of going to "pass out"
- fear of having another episode
- panic attacks in 3 weeks
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What's the # of occurrence and the time frame to diagnose?What's an unusual risk factor for it? besides the obvious ones - ANSWER-Panic Disorder
Risk factor: Neuroticism personality trait
~ This disorder does not have specific genes identified that are associated with it.~ decrease GABA and ACh has been found - ANSWER-Schizophrenia
* Remember its presentation: presence of hallucinations, delusions,
disorganization, and negative symptoms.
- Pathogenesis has multifactorial pathways= genetic + environmental +
physiological.
*Sx must be present for >6 months
Generalized anxiety disorder [GAD] may present with psychological sx, physical sx that at times can mimic a _____.Therefore what should we rule out [3] - ANSWER-GAD physical sx can mimic myocardial infarction.
Also rule out: substance abuse, thyroid fxn, and ETOH withdrawal
Always check: ECG, Troponin --> rule out an MI.
What's the tx for someone who has sudden unexpected periods of intense fear or discomfort? [3] - ANSWER-Panic Disorder
* SSRIs: Paroxetine, Sertraline, Fluoxetine
* Benzos: for acute attacks
- Relaxation, desensitization, examining behavior consequences) 2 / 4
1st line tx for social anxiety disorder
what are the other options...[2] - ANSWER-* 1st line: Cognitive Behavioral
Therapy
** IF it's affecting day to day living: SSRI/SNRI + CBT
if pt is experiencing physical sx: tremors, sweating, palpitation THEN you rx
PROPRANOLOL
#1 A/E: erectile dysfunction! - ANSWER-Selective Serotonin Reuptake Inhibitors
(SSRI)
What's unique about Clozapine? - ANSWER-FIVE BLACK BOX WARNING!
Cardiomyopathy/Myocarditis Orthostatic hypotension Mortality [increase] in elderly w/dementia- psychosis Agranulocytosis - monitor CBC It shows @ beginning of tx) Seizures
"COMAS"
*fyi- ALL pts who are Rx. Clozapine MUST be enrolled in: "Risk Evaluation and Mitigation Strategy program". Clozapine is titrated at a slower rate to mitigate the risk of s/e, including neutropenia.
Pt presents with these sx for more than 6 months: 3 / 4
- poor school performance
- sleep disturbances
- difficulty concentrating, and irritability
What's the 1st line and 2nd line?When does this condition typically begins?
first line for long term treatment of panic disorder? [4] - ANSWER-SSRI:
paroxetine, fluoxetine, sertraline, and venlafaxine
neurotransmitter for depression [4] - ANSWER-* Decreased Serotonin, NE, & dopamine
- INCREASE cortisol
neurotransmitter for Anxiety [3] - ANSWER-1. Decreased GABA, NE & serotonin
neurotransmitter for Bipolar [2] - ANSWER-(+) symptoms = Low dopamine Manic = NE
neurotransmitter for Panic disorder [3] - ANSWER-Decreased GABA & serotonin
INCREASE NE
neurotransmitter for PTSD [1]
what are the two dissociative sx of PTSD? - ANSWER-NT: Decreased serotonin
Dissociative sx:
~ Depersonalization: Feeling detached from one's mental processes or body, so that one feels like an outside observer of one's own experience.
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