HESI Dosage Calculations Practice Exam | 2025/2026 Latest Edition NCLEX-Style Pharmacology & Medication Math | 250 Verified Questions and Answers | 100% Accuracy | Graded A+ Introduction This practice resource includes 250 verified multiple-choice and calculation-based questions from the HESI Dosage Calculations Exam, designed in NCLEX-style format.Updated for the 2025/2026 testing cycle, it covers critical pharmacologic principles, IV calculations, oral dosages, pediatric dosing, conversions, and safe medication administration protocols.Answer Format All correct answers are clearly marked in bold and green for improved accuracy and retention during practice.
Questions
- A patient is prescribed 750 mg of amoxicillin PO every 8 hours. The
- 1 capsule
- 2 capsules
- 3 capsules
- 4 capsules
- 3 capsules
pharmacy provides 250 mg capsules. How many capsules should the patient take per dose?
Rationale: 750 mg ÷ 250 mg/capsule = 3 capsules per dose.
- A medication order calls for 2 g of cefazolin IV. The vial contains 500
- 20 mL
- 30 mL
- 40 mL 1 / 4
mg/10 mL. How many mL should be administered?
- 50 mL
- 40 mL
Rationale: 2 g = 2000 mg. 500 mg/10 mL = 50 mg/mL. 2000 mg ÷ 50 mg/mL = 40 mL.
- A patient is to receive 1000 mL of normal saline over 10 hours. The IV
- 20 gtt/min
- 25 gtt/min
- 30 gtt/min
- 35 gtt/min
- 25 gtt/min
- A patient is prescribed 50 mg of diphenhydramine IV. The vial is
- 1 mL
- 2 mL
- 3 mL
- 4 mL
- 2 mL
tubing has a drop factor of 15 gtt/mL. What is the flow rate in gtt/min?
Rationale: 1000 mL ÷ 10 hours = 100 mL/hr. 100 mL/hr ÷ 60 min = 1.667 mL/min. 1.667 mL/min × 15 gtt/mL ≈ 25 gtt/min.
labeled 25 mg/mL. How many mL should be administered?
Rationale: 50 mg ÷ 25 mg/mL = 2 mL.
- A pediatric patient weighs 20 kg and is prescribed a medication at 10
- 50 mg
- 100 mg
- 150 mg
- 200 mg
- 100 mg
mg/kg/day in two divided doses. How many mg should the patient receive per dose?
Rationale: 20 kg × 10 mg/kg/day = 200 mg/day. 200 mg ÷ 2 doses = 100 mg/dose.
- A patient is to receive 500 mL of D5W over 5 hours. What is the IV flow
rate in mL/hr? 2 / 4
- 75 mL/hr
- 100 mL/hr
- 125 mL/hr
- 150 mL/hr
- 100 mL/hr
Rationale: 500 mL ÷ 5 hours = 100 mL/hr.
- A patient is prescribed 0.5 mg of digoxin IV. The vial contains 0.25
- 1 mL
- 2 mL
- 3 mL
- 4 mL
- 2 mL
mg/mL. How many mL should be administered?
Rationale: 0.5 mg ÷ 0.25 mg/mL = 2 mL.
- A patient is prescribed 12 units of insulin lispro. The vial is labeled 100
- 0.12 mL
- 0.24 mL
- 0.36 mL
- 0.48 mL
- 0.12 mL
units/mL. How many mL should be administered?
Rationale: 12 units ÷ 100 units/mL = 0.12 mL.
- A patient is to receive 600 mL of LR over 4 hours. The IV tubing has a
- 40 gtt/min
- 50 gtt/min
- 60 gtt/min
- 70 gtt/min
- 50 gtt/min
drop factor of 20 gtt/mL. What is the flow rate in gtt/min?
Rationale: 600 mL ÷ 4 hours = 150 mL/hr. 150 mL/hr ÷ 60 min = 2.5 mL/min. 2.5 mL/min × 20 gtt/mL = 50 gtt/min. 3 / 4
- A patient is prescribed 1.5 g of vancomycin IV. The vial contains 500
- 15 mL
- 20 mL
- 25 mL
- 30 mL
- 30 mL
- A pediatric patient weighs 15 kg and is prescribed a medication at 5
- 50 mg
- 75 mg
- 100 mg
- 125 mg
- 75 mg
mg/10 mL. How many mL should be administered?
Rationale: 1.5 g = 1500 mg. 500 mg/10 mL = 50 mg/mL. 1500 mg ÷ 50 mg/mL = 30 mL.
mg/kg. How many mg should the patient receive?
Rationale: 15 kg × 5 mg/kg = 75 mg.
- A patient is to receive 750 mL of normal saline over 6 hours. What is
- 100 mL/hr
- 125 mL/hr
- 150 mL/hr
- 175 mL/hr
- 125 mL/hr
the IV flow rate in mL/hr?
Rationale: 750 mL ÷ 6 hours = 125 mL/hr.
- A patient is prescribed 20 mg of morphine IV. The vial contains 10
- 1 mL
- 2 mL
- 3 mL
- 4 mL
- 2 mL
mg/mL. How many mL should be administered?
Rationale: 20 mg ÷ 10 mg/mL = 2 mL.
- / 4