Exam Newest 2026-2027 CMN 548 Module 5

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CMN 548 Module 5 Psychopharmacology Actual Exam Newest 2026-2027 /CMN 548 Module 5 Psychopharmacology Practice Exam /CMN 548 Module 5 Psychopharmacology Exam Preparation With 200 Questions And Correct Answers| Already Graded A+

Should dopamine blockers be increased to reduce tardive dyskinesia symptoms? - ANSWER-Only if the movements are severe and incapacitating.

• The disorder is most often not progressive and can improve in most

patients.

• Can be switched to dopamine-serotonin antagonists such as clozapine

What are withdrawal emergent dyskinesias? - ANSWER-If patients have their dosages of antipsychotic medication either decreased or discontinued, abnormal movements may worsen temporarily or appear for the first time and then diminish.

Which patient populations are at highest risk for tardive dyskinesia? - ANSWER-- Older women

• Patients with affective disorders
• 10-20% incidence in treatment >1 year 1 / 3

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How often should patients receiving dopamine blockers be evaluated for tardive dyskinesia? - ANSWER-Every 6 months

• Can evaluate severity using the Abnormal Involuntary Movements

Scale (AIMS)

Why does clozapine (Clozaril, DSA antipsychotic) have a lower risk of tardive dyskinesia? - ANSWER-It does not result in the increased sensitivity of striatal D2 receptors, which is associated with typical neuroleptics and has been theorized to result in TD.

What is the mechanism of action of the two medications approved for treatment of Tardive Dyskinesia? - ANSWER-VMAT2 inhibitors

• Can be given in conjunction with antipsychotics

What medication is contraindicaated in the treatment of antipsychotic induced hypotension? - ANSWER-Epinephrine

• due to beta stimulation it worsens hypotension

What is the only dopamine serotonin antagonist (DSA) that is more effective than other antipsychotics at improving overall symptoms? - ANSWER-Clozapine (Clozaril)

• This is why antipsychotics are typically chosen based on side effect

profile

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Olanzapine (Zyprexa, DSA antipsychotic) causes what side effects in children? - ANSWER-- Somnolence

• Liver enzyme elevation
• Prolactin elevation
• Weight gain

*Due to these effects it should be used only when other antipsychotics have failed

Olanzipine (Zyprexa, DSA antipsychotic) has what effect of liver enzymes? - ANSWER-Increases ALT to 3 times the upper limit of normal in 2% of cases

Which medication in the DSA antipsychotic family has a low liability for metabolic side effects? - ANSWER-Lurasidone (Latuda)

• take with food
• potent antagonist at 5-HT2A, D2, and 5-HT7 receptors and a partial

agonist at the 5-HT1A receptor.

• Side effects include sedation, EPS, nausea

Lurasidone (Latuda, DSA antipsychotic) is FDA approved for the treatment of what? - ANSWER-- Schizophrenia in adults

• Adults with bipolar depression as a monotherapy or adjunct to lithium

or valproate

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