EXAM WITH CORRECT SOLUTIONS.

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CSO EXAM

EXAM WITH CORRECT SOLUTIONS.

Hormone Therapy - correct answer- Used to treat hormone sensitive cancers. Stops or reduces the body's ability to produce hormones. Also, substitutes chemically similar agents

for the active hormones that cannot be used by the tumor. Ex:

SERMS, AIs, Progesterones, Antiandrogens, LHRH.

Immunomodulatory Drugs - correct answer- Inhibit anti- inflammatory cytokines and exert anti-angiogenic properties.

Ex: Revlimid, Thaudomide

Adjuvant Therapy - correct answer- The use of additional

cancer treatment given after the primary therapy. Ex: chemo

after lobectomy

Definitive Therapy - correct answer- Prescribed treatment modality with or without additional treatment

Neoadjuvant Therapy - correct answer- The use of one or more treatment modalities given before the primary treatment.

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Biotherapy - correct answer- Treatment to boost or restore the ability of the immune system to fight cancer by inducing, enhancing, or suppressing the immune system response. Also called immunotherapy.

Monoclonal Antibodies - correct answer- Therapies that signal external cellular pathway targets which activate pathways inside. Disrupts cell function and causes cell apoptosis.

Protein Targeted Therapies - correct answer- Therapies the

signal internal cellular pathway that targets proteins. Ex: TKIs,

MTOR inhibitor, Proteasome Inhibitor.

Angiogenesis Inhibitor - correct answer- Hinder the formation of new blood vessels in primary tumors thus preventing their growth, invasion, and spread.

Cytokines - correct answer- Stimulate broad base immune response as opposed to generating a targeted response to specific tumor antigen.

Low Risk of Emesis Chemo - correct answer- Bleomycin 2 / 4

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Busulfan Fludarabine Vinblastine Vincristine Vinorelbine Bevacizumab

Anti-Emetic Drugs - correct answer- 1. Serotonin 5-HT3 (zofran, dolasetron, granisetron, palonsetron)

• Dexamethasone (corticosteroid)
• Aprepitant (NK1 receptor antagonist) Rezonic (casopitant) or

Emend (aprepitant)

Chemo that damages GI Tract - correct answer- Methotrexate Melphalan Irinotecan Fluorouracil

High Risk of Emesis Chemo - correct answer- Cisplatin Mechlorthamine Cyclophosphamide Carmustine 3 / 4

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Dacarbazine

Moderate Risk of Emesis Chemo - correct answer- Oxaliplatin Cytarabine Carboplatin Ifosfamide Cyclophosphamide Doxorubicin Daurorubicin Epirubicin Idarubicin Irinotecan

Beta Carotene - correct answer- Antioxidant

Conventional Food: Carrots, oranges, red/yellow foods

Functional Food: Beta carotene rich juice

B-glucans - correct answer- Natural polysaccharide and soluble fiber that may boost the immune system.

Conventional Food: barley, oats, fruits, vegetables, seaweed.

Functional Food: B-glucan enriched breakfast cereals, breads,

snack bars, bran products, and milk beverages.

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