Final Exam: NR 571 NR571 Latest

Final Exam: NR 571 / NR571 (Latest

Update 2025 / 2026) Complex Diagnosis & Management in Acute Care Practicum | Questions & Answers | Grade A | 100% Correct – Chamberlain

Question:

LFTs to assess for hepatocellular damage

Answer:

ALT, AST, LDH (non-specific)

Question:

LFTs to assess for bile flow interference

Answer:

Bilirubin, alkaline phosphatase, GGT, bile acids, 5'NT

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Question:

ALT

Answer:

alanine aminotransferase

0-32 IU/L

ALT is an enzyme found in high concentrations in the liver that helps convert proteins into energy for the liver cells. More useful at detecting liver pathology.Also found in low concentrations in the kidney and skeletal muscle.>1000 IU/l = extensive hepatocellular injury >3000 IU/L = commonly associated with ischemic liver injury seen in hypoperfusion/shock

Question:

AST/ALT ratio

Answer:

Important in differentiating sources of liver disease An elevated ratio is a strong indicator of alcoholic liver disease AST/ALT ratio <1 as commonly seen in viral hepatitis and fatty liver disease AST/ALT ratio>2 is suggestive of ALD and >3 highly suggestive of ALD

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Question:

Markers of cholestatic disorders

Answer:

ALP, GGT, total bilirubin,

Question:

Elevated AST/ALT in the asymptomatic patient

Answer:

No further work up if no clear risk factor for liver disease, AST and ALT are less than three times normal, liver function (serum albumin, PT, and bilirubin) as preserved, and patient feels well.If these conditions are not met or repeat testing shows persistent elevation, further testing should be considered (abdominal CT, ultrasound, etc)

Question:

Possible causes of acute hepatocellular injury

Answer:

Acute viral hepatitis, alcoholic hepatitis, ischemic injury, toxin or drug induced injury

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Question:

AST

Answer:

aspartate aminotransferase

0-40 IU/L

AST is an enzyme that helps the body break down amino acids.

It's found in the liver, heart muscles, skeletal muscles, kidney, brain, pancreas, lungs, WBC, RBC's.

More sensitive than ALT in detecting, alcohol induced disease

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