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Final Exam: NU643 / NU 643 (Latest
Update 2025 / 2026) Advanced Psychopharmacology | Guide Questions and Answers | Grade A | 100% Correct - Regis
Question:
Inverse agonist binding
Answer:
Cause inactivation of signal transduction
Question:
A neurotransmitter binds to a receptor
Answer:
Causing electrical impulses to travel the neuron's axon; it eventually releases the neurotransmitter and repeats the process with a postsynaptic neuron, classical synaptic neurotransmission
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Question:
True of pharmacokinetics’
Answer:
Accumulation of psychotropic drugs occurs faster in the brain than adipose tissue
Question:
CYP450 TABLE
Answer:
Inhibitors and substrates INCREASE effectiveness of drug metabolized inducers DECREASE effectiveness
Question:
Two main targets of signal transduction
Answer:
Gene expression and phosphoproteins
Question:
Antagonist binding to receptor
Answer:
Unchanged signal transduction 2 / 4
Question:
First pass effect
Answer:
Metabolism of the drug in the liver, prior to reaching systemic circulation
Question:
Partial agonist binding to receptor
Answer:
Signal transduction is partially enhanced
Question:
Phase 1 metabolism
Answer:
CYP450 enzyme activity
Question:
Phase 2 metabolism
Answer:
Conjugation of drug
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Question:
G-linked proteins
Answer:
Bind enzymes that synthesize second messenger
Question:
Enzyme inhibition as a target of drug therapies
Answer:
A means of preventing the degradation of neurotransmitters
Question:
Ligand-gated ion channel
Answer:
Allosteric modulators can enhance or inhibit ion channels when in the presence of neurotransmitter
Question:
Agonist binding to receptor
Answer:
Singal transduction is fully enhanced antagonist, in the presence of an agonist, can return a channel to resting state
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