Final Exam: NU664C NU 664C

Final Exam: NU664C / NU 664C

(Latest Update 2025 / 2026) Family Psychiatric Mental Health I | Test Questions & Answers | Grade A | 100% Correct (Verified Answers) - Regis

Question:

SSRIs and other serotonergic antidepressants are effective in the treatment of

Answer:

depression, other data indicate that serotonin is involved in the pathophysiology of depression

Question:

Depletion of serotonin may

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precipitate depression, and some patients with suicidal impulses have low cerebrospinal fluid (CSF) concentrations of serotonin metabolites and low concentrations of serotonin uptake sites on platelets.

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Question:

Although norepinephrine and serotonin are the biogenic amines most often associated with the pathophysiology of depression,

Answer:

dopamine has also been theorized to play a role. The data suggest that dopamine activity may be reduced in depression and increased in mania

Question:

Drugs that reduce dopamine concentrations—for example, reserpine (Serpasil)—

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and diseases that reduce dopamine concentrations (e.g., Parkinson's disease) are associated with depressive symptoms

Question:

Drugs that increase dopamine concentrations

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such as tyrosine, amphetamine, and bupropion (Wellbutrin), reduce the symptoms of depression

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Question:

Two recent theories about dopamine and depression are that

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the mesolimbic dopamine pathway may be dysfunctional in depression and that the dopamine D1 receptor may be hypoactive in depression

Question:

Neurotransmitter Disturbances Acetylcholine (ACh) Abnormal levels of choline, which is a precursor to ACh, have been found at

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autopsy in the brains of some depressed patients, perhaps reflecting abnormalities in cell phospholipid composition

Question:

Reductions of GABA have been observed in

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CSF, and brain GABA levels in depression. Animal studies have also found that chronic stress can reduce and eventually can deplete GABA levels. By contrast, GABA receptors are upregulated by antidepressants, and some GABAergic medications have weak antidepressant effects

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Question:

Serotonin syndrome

Answer:

Concurrent administration of an SSRI with an MAOI, Ltryptophan, or lithium (Eskalith) can raise plasma serotonin concentrations to toxic levels, producing a constellation of symptoms called serotonin syndrome.

Question:

This serious and possibly fatal syndrome of serotonin overstimulation comprises, in order of appearance as the condition worsens

Answer:

(1) diarrhea;

(2) restlessness;

(3) extreme agitation, hyperreflexia, and autonomic instability with possible rapid fluctuations in vital signs;

(4) myoclonus, seizures, hyperthermia, uncontrollable shivering, and rigidity;

(5) delirium, coma, status epilepticus, cardiovascular collapse, and death.

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