FREE AND STUDY GAMES ABOUT CH 20 PHARMACOLOGY I

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FREE AND STUDY GAMES ABOUT CH 20 PHARMACOLOGY I

EXAM QUESTIONS

Actual Qs and Ans Expert-Verified Explanation

This Exam contains:

-Guarantee passing score -33 Questions and Answers -format set of multiple-choice -Expert-Verified Explanation Question 1: One of the three measure of the rate and extent of drug absorption, with Cmax (maximum plasma concentration achieved) and Tmax (time of the maximum plasma concentration.)

Answer:

AREA UNDER THE PLASMA CONCENTRATION-TIME CURVE (AUC).

Question 2: Method for the drugs to enter the body's circulation.

Answer:

ABSORPTION.

Question 3: Define elimination half-life.

Answer:

The amount of time it takes to eliminate one-half of the total amount of drug in the blood.Question 4: The purpose of this process is to convert the drug molecule to more water-soluble and inactive metabolites.

Answer:

METABOLISM.

Question 5: The type of drug administration that can be administered via injection into the vein

is called:

Answer:

Intravascular administration.

Question 6: Define first-pass metabolism.

Answer:

Occurs when a drug is rapidly metabolized in the liver after oral administration with minimum bioavailability.Question 7: The fraction of an administered dose that ultimately reaches the system or whole body circulation is defined by this term.

Answer:

Bioavailability.

Question 8: Movement of the drug from the blood to other body tissues.

Answer:

DISTRIBUTION.

Question 9: If 1,000 mg of a drug is administered in an oral tablet and 400 mg of the drug is absorbed into the the systemic circulation, then the absolute bioavailability (F) is:

Answer:

Forty percent.Question 10: These types of studies are bioavailability studies specifically comparing two or more formulations of the same dose of the same drug in the same dosage form.

Answer:

Bioequivalence.

Question 11: Define absorption.

Answer:

The fraction of an administered drug that reaches the systemic circulation.

Question 12: The bioavailability of a drug administered intravenously is:

Answer:

100 percent.

Question 13: Define metabolism.

Answer:

The process by which an organism converts food to energy needed for anabolism.

Question 14: Define AUC - Area under the plasma concentration-time curve.

Answer:

Plasma drug concentration can be determined by calculating the rate and extent of systemic absorption, as visualized by the plasma concentration-time curve.Question 15: List the correct order of events an oral dosage form must go through for the drug

to reach the bloodstream:

Answer:

Disintegration, dissolution, diffusion.

Question 16: Define T-max.

Answer:

In biopharmaceutics, it indicates how long it takes to reach maximum drug concentration in the body's circulation.Question 17: The bioavailability of an oral tablet could be decreased due to:

Answer:

Incomplete dissolution, incomplete diffusion, and first-pass metabolism.Question 18: The type of drug administration that can be via oral, rectal, intramuscular, buccal, subcutaneous, transdermal or percutaneous, pulmonary or inhalation, intranasal administration

is called:

Answer:

Extravascular administration.

Question 19: Define bioavailability.

Answer:

The term used to indicate the rate and relative amount of administered drug that reaches the circulatory system intact.Question 20: This state of drug product must disintegrate into smaller particles so the drug can be released from the formulation.

Answer:

Solid.Question 21: Bioavailability is defined as:

Answer:

The fraction of an administered dose that reaches the systemic circulation.Question 22: The movement of the drug from the bloodstream to other bodily tissues is called:

Answer:

Distribution.

Question 23: Name the two categories of drug administration.

Answer:

Intravascular and extravascular.Question 24: Examples of extravascular routes of administration include:

Answer:

Subcutaneous and Intravenous.

Question 25: Define bioequivalence.

Answer:

The comparison of the bioavailability of different drug products with the same active ingredient.

Question 26: Define elimination.

Answer:

The removal of waste material from the body.