GERD - CMPP Exam 6 Latest Update - Actual Exam Questions and 100% Verified Correct Answers Guaranteed A+
80% of all peptic strictures are secondary to ___ - CORRECT ANSWER: GERD
For Pts with 2 or more episodes per week and/or severe symptoms interfering with quality of life... - CORRECT ANSWER: Step 1: PPI once or twice daily for 8 weeks in addition to diet and lifestyle modifications
Step 2: If symptoms controlled, step down to lower dose PPI, then eventually to H2 or lifestyle modifications alone
How are PPIs more effective than H2 blockers? - CORRECT ANSWER: act on final
pathway of acid rather than specific receptor
Relieve symptoms and heal esophagitis in 85-90% of patients
How can GERD be classified? - CORRECT ANSWER: by endoscopic appearance
How do long-term use of PPIs cause infection? - CORRECT ANSWER: Chronic
suppression of acid Raises concern for increased risk of enteric infections including GI bugs (Salmonella, Campylobacter) and infectious diarrhea Allows more colonization of the upper GI tract
How do peptic strictures form? - CORRECT ANSWER: Usually results from the healing process of ulcerative esophagitis related to uncontrolled GERD Collagen deposited during healing phase of esophagitis which contract over time and narrow the lumen
more commonly at GEJ
How do PPIs affect Ca absorption? - CORRECT ANSWER: Hypochlorhydria (low HCl
levels due to PPI) Theoretically reduces calcium absorption = decreased bone density
How do PPIs cause kidney disease? - CORRECT ANSWER: PPIs are known to cause
Acute Interstitial Nephritis (AIN)
Weak association seen in some studies associating PPI use with increased risk of incident CKD, CKD progression, and end-stage renal disease (ESRD)
How do you diagnose barrett's esophagus? - CORRECT ANSWER: Endoscopy 1 / 2
Sensitivity of endoscopy to detect Barrett's depends on the length of the mucosa involved
How do you diagnose peptic strictures? - CORRECT ANSWER: endoscopy - can be
both diagnostic and therapeutic barrow swallow - if suspicion for complex stricture
How do you manage post-op dysphagia? - CORRECT ANSWER: liquid diet for 2-12
weeks If persists more than 12 weeks, barium swallow to evaluate placement of fundoplication (may need dilation)
How do you manage post-op Gas-Bloat Syndrome? - CORRECT ANSWER:
simethicone tablets (Gas-X), avoid carbonation, metoclopramide (Reglan) to promote gastric motility
may be if large wrap done or wrap is too tight
How do you treat dysplasia + Barrett's? - CORRECT ANSWER: Endoscopic eradication with radiofrequency ablation (RFA), photodynamic therapy or endoscopic mucosal resection (EMR) is recommended for HIGH GRADE dysplasia Esophagectomy in severe cases
How do you treat GERD + Barrett's ? - CORRECT ANSWER: Step-up' therapy not
appropriate
Should start with standard dose of PPI
Goal of treatment:
Control symptoms Patients with long-segment Barrett's can have more difficult to treat symptoms May need PPI QAM, H2 blocker QPM or PPI BID
NOTE: this approach is to control symptoms but has not been proven to prevent
progression to cancer
How do you treat peptic strictures? - CORRECT ANSWER: Endoscopic Dilation of
stricture May require multiple, progressive attempts
NO ROLE FOR STENTING
Medication Treatment with acid reduction (PPI or H2 blockers) is needed to prevent recurrence, regardless of GERD symptoms
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