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Midterm Exam: NR 546 / NR546
(Latest Update 2025 / 2026)
Advanced Pharmacology:
Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner | Questions and Answers | 100% Correct | Grade A - Chamberlain
Question:
What is neurolepsis?
Answer:
A term describing antipsychotic medication effects on cognition and behavior in psychotic clients.
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Question:
What are the desirable effects of first-generation antipsychotics (FGAs)?
Answer:
They improve positive symptoms of acute and chronic schizophrenia and psychosis.
Question:
What are the undesirable effects of FGAs?
Answer:
They can cause hyperprolactinemia and extrapyramidal symptoms.
Question:
What is the risk associated with long-term use of typical antipsychotics?
Answer:
Failure to discontinue can result in permanent tardive dyskinesia.
Question:
What are the common adverse effects of excessive D2 receptor blockade?
Answer:
Cardiac concerns, blood dyscrasias, esophageal dysmotility, and increased fall risk. 2 / 4
Question:
What are commonly prescribed first-generation antipsychotics?
Answer:
Chlorpromazine, Mesoridazine, Thioridazine, Thiothixene, Fluphenazine, and Haloperidol.
Question:
What distinguishes second-generation antipsychotics (SGAs) from FGAs?
Answer:
SGAs treat both positive and negative symptoms of psychosis, while FGAs primarily address positive symptoms.
Question:
What are second-generation antipsychotics (SGAs) primarily used to treat?
Answer:
Both positive and negative symptoms of psychosis.
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Question:
How do SGAs differ from first-generation antipsychotics (FGAs) in terms of side effects?
Answer:
SGAs generally have fewer extrapyramidal symptoms (EPS) and prolactin effects than FGAs.
Question:
What is the mechanism of action for SGAs?
Answer:
They act as serotonin-dopamine antagonists, maintaining D2 antagonism while also antagonizing serotonin 5HT2A.
Question:
What effect does stimulation of 5HT1A receptors have on dopamine release?
Answer:
It increases dopamine release.
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