MMSC 407 Clinical Chemistry Actual Final Exam

MMSC 407 Clinical Chemistry (Actual )Final Exam Questions with 100% verified Correct Answers/Update| Grade A+

if you have a non fasting specimen, and it is lipemic/cloudy, you are looking at___ -----Answers----chylomicrons

Endogenous pathway of lipoprotein metabolism ----- Answers----VLDL will be hydrolyzed into IDL through interactions w/ lipo. lipase and HDL a loss of triglycerides

IDL is converted into LDL through interactions with __ and __. - ----Answers----HDL and LCAT

LDL transports cholesterol to the tissues to help with: -----

Answers----steroid synthesis cell membrane synthesis

LDL can be catabolized by Either: -----Answers----liver or

tissue cells

in the tissue, LDL gets engulfed by cells and degraded by: ----

-Answers----lysosomes

atherosclerosis -----Answers----deposition of fatty streaks, plaque 1 / 4

made up of cholesterol and cholesterol esters

PVD -----Answers----plaque that builds up in the arms or legs

CAD -----Answers----plaque that builds up in the arteries leading to the heart

CVD -----Answers----plaque that builds up in the vessels of the brain, leading to stroke

what are 2 reasons atherosclerosis occurs? -----Answers--- -injury to arterial lining abundance of cholesterol

*smoking, high BP, viral infection, increased LDL oxidation*

why does injury cause plaque formation? -----Answers---- macrophages and platelets are drawn to the site of injury to repair the tissues

triglyceride referenece ranges -----Answers----acceptable:

60-150 mg/dL

borderline high: 150-200

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triglyceride clinical significance; -----Answers----inherited

traits: defected LDL receptors

• main sources of cholesterol -----Answers----diet

biliary secretion intestinal mucosal cell secretion

a 12 hour ___ method is required for total cholesterol specimen -----Answers----fasting

What are two ways we can measure total cholesterol in sample? -----Answers----measure oxygen consumption or measure color change as an endpoint rxn

healthy reference range of total cholesterol for adults: -----

Answers----<200mg/dL

coronary heart disease risk increases as LDL cholesterol ____ HDL cholesterol ____ -----Answers----increases decreases

primary CHD risk factors -----Answers----genetics smoking high BP 3 / 4

secondary CHD risk factors -----Answers----lack of exercise obesity age stress gender oral contraceptives

HDL cholesterol methods -----Answers----precipitation methods homogenous enzymatic method

LDL measurement -----Answers----friedewald calculation homogenous enzyme methods

reference ranges for LDL -----Answers----<130 mg/dL

what is the most common lipoprotein electrophoresis support medium? -----Answers----agarose gel

what is noted as an additional risk factor for CHD and CVD? --- --Answers----Lp(a)

metabolic syndrome -----Answers----group of risk factors for development of cardiovascular disease or Diabetes type II

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