Nagelhout-Pharm 2-Exam 1 (Actual / ) UPDATED 122 Questions And 100% Verified CORRECT Answers
Ultra short acting neuromuscular blocker (Length of duration) Succinylcholine (5 - 15 minutes)
Depolarizing NMB Succinylcholine
Posttetanic Count Test 50 Hz stimulus for 5 sec → 3 sec pause → 1 Hz single twitch every second Only used when patient is 100% paralyzed More post-tetanic twitches = closer to recovery
Sequence of muscle paralysis
- Eyelids (Protective muscles of pharynx)
- Extremities
- Chest (neck downward) 1 / 4
- Abdominal muscles
- Diaphragm
Muscles not affected by NMBs (4)
- Cardiac muscle
Smooth muscle:
- Bronchi (can't treat bronchospasm with NMBs)
- Uterus
- GI/bowels
Peripheral nerve stimulator should be at least ___ mA 30
Cisatracurium doses
1. ED95
- Intubating dose
- Time to onset
- Duration of action
- 0.05 mg/kg
- 0.1 mg/kg
- 2-4 minutes
- Intermediate, 30-60 minutes 2 / 4
Rocuromium doses
1. ED95
- Intubating dose
- Time to onset
- Duration of action
- 0.3 mg/kg
- 1 mg/kg
- 1-3 minutes**
- Intermediate, 30-60 minutes
Vecuronium doses
1. ED95
- Intubating dose
- Time to onset
- Duration of action
- 0.05 mg/kg
- 0.1 mg/kg
- 2-4 minutes
- Intermediate, 30-60 minutes
- / 4
Pancuronium doses
1. ED95
- Intubating dose
- Time to onset
- Duration of action
- 0.05 mg/kg
- 0.08-1.8 mg/kg
- 2-4 minutes
- Long, 60-90
Clinical signs of recovery from NMB (14)
- Adequate tidal volume
- Respirations smooth unlabored
- Opens eyes widely, no diplopia
- Sustained protrusion/purposeful tongue movement
- Effective swallowing/bite
- Sustain head for 5 sec
- Arm lift, touch opposite shoulder
- Strong hand grip
- Effective cough
- Adequate vital capacity (15mL/kg)
- Adequate inspiratory force (25-30 cm H2O neg. pressure)
- Sustained tetanic response (no fade x5 sec)
- / 4