NBME CBSE STEP 1 ACTUAL EXAM LATEST

NBME CBSE STEP 1 (ACTUAL / ) EXAM LATEST

QUESTIONS AND VERIFIED ANSWERS GRADED A+!.

Reactive Arthritis caused by -----Answers----Chlamydia

GI: Salmonella, Shigella (M cells), Yersinia, Campy, C dif

Shigella invades -----Answers----M cells (peyer's patches, MALT)

Chlamydia histo -----Answers----cytoplasmic inclusion bodies in epithelial and leukocytes

Reactive arthritis -----Answers----Urethrtiis Arthritis (sterile joint aspiration) Conjunctivitis Sacrolilitis

tx C dif -----Answers----Fidaxomicin (macrolide) Oral Vancomycin IV Metronidazole

Tb: CD___ is on ______ -----Answers----CD 14 on epitheliod

macrophages 1 / 4

Virulence of Tb -----Answers----Cord factor --> Caseating granulomas

Tb activates what cells (+ cytokines) -----Answers----*CD4* = IFNg and IL-12 --> *macrophage*

which cytokine is related to IFN-g -----Answers----IL-12 (*NK)

Tb: what do IFN-a and IFN-B do? -----Answers----*halt

protein synth* of virus

released from viral infected *epithelial* cells

Reactivation of Tb location -----Answers----upper lobes (due to high V/Q ratio)

Tb and Aspergillus -----Answers----Aspergillus COLONIZES cavities --> fungus ball

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how does Aspergillus disseminate -----Answers----vascular invasion

• whipple -----Answers----Intestine + Joints + CNS

proliferates in *macrophages* PAS+ (glycoprotein)

What is found in appendicitis abscess -----Answers---- bacteroides

Borrelia stages: symptoms/tx -----Answers----1. erythema

migrans

• Doxycylcine
• Facial palsy
• Ceftriaxone
• asymmetric migratory arthritis and encephalopathy

What is required to make PG cell wall -----Answers---- glycosyltransferase

What bacteria does not have a cell wall -----Answers---- Mycoplasma

Hemolytic uremic syndrome -----Answers----Shigella + E

Coli (O157:H7)

= bloody diarrhea 3 / 4

= Thrombocytopenia *Microthrombi in small bv *--> AKI increased *indirect bilirubin & LDH*, decreased Hgb & haptoglobin

what can HUS cause in kidney -----Answers---- *microthrombi* in small bv = Acute Kidney Injury (hematuria)

bacteremia in a sickle cell patient -----Answers----SEPSIS

*Strep pneumo; *H.flu

Bacterial Meningitis bugs -----Answers----*Strep pneumo* > Neisseria

Neonate: *Strep galacto* > E coli > Listeria

*Listeria *= baby/elder - tx: ampicillin

H flu (has *vaccine* now!!!!) *Staph post-op*

tx for N/V from bacteria -----Answers----*Ondansetron* (5HT3-R antagonist)

GI irritation causes serotonin release

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