NSG 520 Final Latest Update -

NSG 520 Final Latest Update - Exam 400 Questions and 100% Verified Correct Answers Guaranteed A+ Approved by the Professor

2 resources for drug shortages - CORRECT ANSWER: FDA drug shortages website

ASHP drug shortage website

• specific properties for successful transdermal and dermal delivery - CORRECT

ANSWER: <600 Da

low melting point large drug dose

35 year old female living with HIV presents to the infectious disease clinic with a two week history of white plaques in her mouth and painful swallowing. She has a history of poor adherence to antiretrovirals the doctor would like to prescribe fluconazole 100 milligrams daily for esophageal Candidiasis and asks you, the clinical pharmacist, if

tablets are the only option. You check the fluconazole monograph:

solution, IV: 100mg, 200mg, 400mg

suspension reconstituted, oral: 10mg/mL, 40mg/mL

tablet, oral: 50mg, 100mg, 150mg, 200mg

Your recommendation is

• she will just have to deal with swallowing tablets
• only alternative is IV solution so she will have to be admitted to the hospital
• the pharmacy can compound an extemporaneous suspension
• prescribe 2.5 mL of the 40 mg/mL oral suspension daily to equate 100 mg
• prescribe 100 mL of the 10 mg/mL oral suspension daily to equate 100 mg -

CORRECT ANSWER: D

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4 advantages of liposomes for ocular delivery - CORRECT ANSWER: enhanced

bioavailability controlled release targeted delivery improved efficacy

A 24 year old female is recovering in the intensive care unit after a motor vehicle accident. She is mechanically ventilated and recently had an enteral tube placed for enteral feedings. She is prescribed multiple medications in the team asks you if any can be administered via the enteral tube. This is / these are general considerations

regarding enteral tube administration of medications:

• compatibility of the medication with tube feedings
• PH dependent dissolution of the medication
• accuracy of medication dosing

D. all of the above - CORRECT ANSWER: D

A 65 year old male with a history of diabetes and hypertension is in the neurology intensive care unit for observation following a cerebral vascular incident. He was given tissue plasminogen activator TPA alteplase upon presentation to the emergency Department. He regained a significant amount of functioning but is still experiencing dysphasia. The team asks you, the clinical pharmacist, if his medications can be crushed and mixed with applesauce for administration. The first stop on your literature search is the do not crush list. The organization that maintains this list is the:

• Institute for safe medication practices
• Food and Drug administration
• United States pharmacopoeia

D. American Heart Association - CORRECT ANSWER: A

accumulation of triglyceride particles at the top of an emulsion - CORRECT ANSWER: creaming

an IV solution has a shelf life of 5 hours at room temp (25 degrees C). what is the shelf if stored int he fridge at 5 degrees C? - CORRECT ANSWER: 5/3^((5-25)/10) 2 / 4

45 hours

an oral suspension has a shelf life of 48h at 5 degrees C. what is the estimated shelf life

at room temp (25 degrees C)? Use Q value of 3 - CORRECT ANSWER: 48/3^((25-

5)/10)

5.33 hours

are the following dosage forms considered single-unit or multiple unit?capsule granule pellet tablet

mini-tablet - CORRECT ANSWER: single

multi multi single multi

average skin (epidermis and dermis) thickness - CORRECT ANSWER: 2.1mm

batches of less than 25 high-risk compounded products do not require sterility testing -

CORRECT ANSWER: t

BUD for nonsterile nonaqueous formulations - CORRECT ANSWER: 6 months

BUD for nonsterile water containing oral form - CORRECT ANSWER: 14 days stored in fridge

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BUD for water-containing topical/dermal and mucosal liquid and semisolid formulations - CORRECT ANSWER: 30 days or the intended duration of therapy (as long as it's less than 30 days)

BUD or exp date?

based on analytical and performance testing - CORRECT ANSWER: exp date

BUD or exp date?chemical and physical stability of manufactured (sterile) products - CORRECT

ANSWER: exp date

circulation life for liposomes - CORRECT ANSWER: more than 5 hour half-life, long circulation life

color changes or precipitation are indicative or which type of incompatibility - CORRECT

ANSWER: physical

creaming or cracking of lipids may occur in which scenario - CORRECT ANSWER:

lipids mixed into TPN (3-in-1)

define extemporaneous - CORRECT ANSWER: impromptu

prepared without a standard formula from an official compendium prepared as required for a specific patient

define personalized medicine - CORRECT ANSWER: pts receive meds tailored for them rather than the same drug at the same dose

describe the difference between adverse events and adverse drug reactions -

CORRECT ANSWER: AE have an unknown cause

ADR = drug is cause

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