NSG 6005 WEEK 8 QUIZ TEST BANK WITH 100

NSG 6005 WEEK 8 QUIZ TEST BANK WITH 100

ACTUAL QUIZ QUESTIONS WITH 100% CORRECT

VERIFIED ANSWERS ALREADY GRADED A+ SOUTH

UNIVERSITY/ NSG 6005 ADVANCED

PHARMACOLOGY EXAM (WEEK 8) LATEST

Lispro is an insulin analogue produced by recombinant deoxyribonucleic acid (DNA) technology. Which of the following statements about this form of insulin is not true?

• The optimal time of preprandial injection is fifteen minutes.
• The duration of action is increased when the dose is increased.
• It is compatible with NPH insulin.
• It has no pronounced peak. - ANSWER-B. The duration of action is increased

when the dose is increased.

DPP-4 inhibitors (gliptins) act on the incretin system to improve glycemic control.

Advantages of these drugs include:

• Better reduction in glucose levels than other classes
• Less weight gain than sulfonylureas
• Low risk for hypoglycemia
• Can be given twice daily - ANSWER-C. Low risk for hypoglycemia

When the total daily insulin dose is split and given twice daily, which of the following rules may be followed?

• Give two-thirds of the total dose in the morning and one-third in the evening. 1 / 4

• Give 0.3 units/kg of premixed 70/30 insulin, with one-third in the morning and

two-thirds in the evening.

• Give 50% of an insulin glargine dose in the morning and 50% in the evening.
• Give long-acting insulin in the morning and short-acting insulin at bedtime. -

ANSWER-A. Give two-thirds of the total dose in the morning and one-third in the evening.

Sitagliptin has been approved for:

• Monotherapy in once-daily doses
• Combination therapy with metformin
• Both A and B
• Neither A nor B - ANSWER-C. Both A and B

When blood glucose levels are difficult to control in type II diabetes, some form of insulin may be added to the treatment regimen to control blood glucose and limit complications risks. Which of the following statements are accurate based on research?

• Premixed insulin analogues are better at lowering hemoglobin A1c and have

less risk for hypoglycemia.

• Premixed insulin analogues and the newer premixed insulins are associated with

more weight gain than the oral antidiabetic agents.

• Newer premixed insulins are better at lowering hemoglobin A1c and

postprandial glucose levels than are long-acting insulins.

• Patients who are not controlled on oral agents and have postprandial

hyperglycemia can have NPH insulin added at bedtime. - ANSWER-C. Newer premixed insulins are better at lowering hemoglobin A1c and postprandial glucose levels than are long-acting insulins.

• / 4

The American Diabetic Association has recommended which of the following tests for ongoing management of diabetes?

• Fasting blood glucose
• Hemoglobin A1c
• Thyroid function tests
• Electrocardiograms - ANSWER-B. Hemoglobin A1c

Adam has type I diabetes and plays tennis for his university. He exhibits a knowledge deficit about his insulin and his diagnosis. He should be taught that:

• He should increase his CHO intake during times of exercise.
• Each brand of insulin is equal in bioavailability, so buy the least expensive.
• Alcohol produces hypoglycemia and can help control his diabetes when taken in

small amounts.

• If he does not want to learn to give himself injections, he may substitute an oral

hypoglycemic to control his diabetes. - ANSWER-A. He should increase his CHO intake during times of exercise.

Unlike most type II diabetics where obesity is a major issue, older adults with low body weight have higher risks for morbidity and mortality. The most reliable

indicator of poor nutritional status in older adults is:

• Weight loss in previously overweight persons
• Involuntary loss of 10% of body weight in less than six months
• Decline in lean body mass over a twelve-month period
• Increase in central versus peripheral body adiposity - ANSWER-B. Involuntary

loss of 10% of body weight in less than six months 3 / 4

Insulin is used to treat both types of diabetes. It acts by:

• Increasing beta cell response to low blood glucose levels
• Stimulating hepatic glucose production
• Increasing peripheral glucose uptake by skeletal muscle and fat
• Improving the circulation of free fatty acids - ANSWER-C. Increasing

peripheral glucose uptake by skeletal muscle and fat

Control targets for patients with diabetes include:

• Hemoglobin A1c between 7 and 8
• Fasting blood glucose levels between 100 and 120 mg/dl
• Blood pressure less than 130/80 mm Hg
• LDL lipids less than 130 mg/dl - ANSWER-C. Blood pressure less than 130/80

mm Hg

Hypoglycemia can result from the action of either insulin or an oral hypoglycemic.

Signs and symptoms of hypoglycemia include:

• "Fruity" breath odor and rapid respiration
• Diarrhea, abdominal pain, weight loss, and hypertension
• Dizziness, confusion, diaphoresis, and tachycardia
• Easy bruising, palpitations, cardiac dysrhythmias, and coma - ANSWER-C.

Dizziness, confusion, diaphoresis, and tachycardia

• / 4